Antibacterial activity of pyrrolidine dithiocarbamate. [PDF]
FEMS microbiology letters, 2008 Pyrrolidine dithiocarbamate (PDTC), an antioxidant with a metal-chelating activity, has been used widely to inhibit the expression of inflammatory genes in vitro and in vivo. This study investigated whether PDTC has an antimicrobial activity against various bacteria.
Mi-Sun, Kang +12 more
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Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation. [PDF]
J Pharmacol Exp Ther, 2011 Song S +5 more
europepmc +3 more sources
Simultaneous Determination of Mixed Heavy Metal Ions Cr (III) and Co (II) in Wastewater by Cloud Point Extraction Dual Wavelength Spectrophotometry [PDF]
E3S Web of Conferences, 2023 Using cloud point extraction technology and the principle of absorbance addition in multi-component system, the mixed metal ions Cr (III) and Co (II) in industrial wastewater were enriched and determined at pH 5.0 and 50℃, using ammonium pyrrolidine ...
Liu Hongmei, Xie Jun, Qian Hongming
doaj +1 more source
Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. [PDF]
Neuroscience, 2014 Zhang J, Jiang W, Zuo Z.
europepmc +2 more sources
Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis
Experimental Cell Research, 2004 Proteasomes play important roles in a variety of cellular processes such as cell cycle progression, signal transduction and immune responses. Proteasome activity is important in maintaining rapid turnover of short-lived proteins, as well as preventing accumulation of misfolded or damaged proteins.
In‐Sook Kim +9 more
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Pyrrolidine dithiocarbamates of Pd(II) [PDF]
Inorganica Chimica Acta, 2005 The dithioester (CH2)4NCS2CH3 (PyDTM, 1-pyrrolidinecarbodithioate methyl ester) has been prepared by reaction of the parent ammonium salt NH4PyDT (PyDT=(CH2)4NCS2 with methyl iodide in water/ethanol. The reaction of PyDTM with PdCl2 allowed to synthesize either (PdCl2(PyDTM)), in which the ligand is chelated by both sulfur atoms, or(PdCl2(PyDTM)2), in ...
Faraglia, Guiseppina +2 more
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Pyrrolidine dithiocarbamate attenuates paraquat-induced lung injury in rats. [PDF]
J Biomed Biotechnol, 2009 Paraquat (PQ) has been demonstrated that the main target organ for the toxicity is the lung. This study aimed to investigate the potential protective effect of PDTC on the PQ‐induced pulmonary damage. Fifty‐four rats were divided into control, PQ‐treated and PQ+PDTC‐treated groups.
Chang X +5 more
europepmc +4 more sources
Pyrrolidine dithiocarbamate down-regulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodelling in renovascular hypertension. [PDF]
Br J Pharmacol, 2011 Cau SB +7 more
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Pre‐Clinical Safety Evaluation of Pyrrolidine Dithiocarbamate [PDF]
Basic & Clinical Pharmacology & Toxicology, 2010 Abstract: Pyrrolidine dithiocarbamate (PDTC) was examined for its potential in the intranasal treatment of human rhinovirus infections. Prior to clinical testing, a comprehensive non‐clinical programme was performed to evaluate the general toxicity of PDTC.
Monika, Chabicovsky +6 more
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