Results 251 to 260 of about 17,768 (339)

Reply to Piehler et al.: Depression Symptoms in Patients with Cystic Fibrosis Fluctuate at Baseline and Improve with Elexacaftor/Tezacaftor/Ivacaftor Therapy. [PDF]

Am J Respir Crit Care Med
Duff AJA, Lee TWR.
europepmc   +1 more source

Two New Pyrrolidine Alkaloids, Radicamines A and B, as Inhibitors of .ALPHA.-Glucosidase from Lobelia chinensis LOUR.

, 2001
Makio Shibano, Daisuke Tsukamoto, Atsuko Masuda, Yasuko Tanaka, Genjiro Kusano   +4 more
openalex   +2 more sources

Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

The FEBS Journal, EarlyView.
Compounds were identified that inhibit the aspartic protease plasmepsin V from Plasmodium vivax. Further development of these compounds identified compounds, such as S‐WM48, that could inhibit both plasmepsin V and plasmepsin X but plasmepsin IX was not significantly inhibited.
Anthony N. Hodder, Brad E. Sleebs, Greg Adams, Sina Rezazadeh, Anna Ngo, Kate Jarman, Stephen Scally, Peter Czabotar, Hongwu Wang, John A. McCauley, David B. Olsen, Alan F. Cowman   +11 more
wiley   +1 more source

Borohydride Oxidation as Counter Reaction in Reductive Electrosynthesis

Angewandte Chemie, Volume 137, Issue 20, May 12, 2025.
Herein, anodic borohydride oxidation is demonstrated to have great potential for successfully replacing sacrificial metal anodes in a variety of electroreductive organic transformations. This anodic counter reaction effectively serves as the inverse of cathodic proton reduction, producing H2 at inert carbon‐based electrode materials.
Julius Kuzmin, Malin Lill, Guillermo Ahumada, Ellymay Goossens, Astrid Kjær Steffensen, Anders Riisager, Helena Lundberg   +6 more
wiley   +2 more sources

Revisiting the 1,3-azadiene-succinic anhydride annulation reaction for the stereocontrolled synthesis of allylic 2-oxopyrrolidines bearing up to four contiguous stereocenters. [PDF]

RSC Adv
Beng TK, Kaur J, Anosike IS, Rentfro B, Newgard S.   +4 more
europepmc   +1 more source

Cyclic Bifunctional Reagents Enabling a Strain-Release-Driven Formal [3 + 2] Cycloaddition of 2<i>H</i>-Azirines by Cascade Energy Transfer. [PDF]

J Am Chem Soc
Petti A, Karrasch MJ, Chahar P, Wessels FH, Hölter N, Boser F, Daniliuc CG, Glorius F.   +7 more
europepmc   +1 more source

Caractère énamine comparé des (pyrrolidine-1 yl) et (morpholine-1yl)-3benzo (b) furanne, -thiophène et sélénophène

, 1975
Jean-Frédéric F. Weber
openalex   +1 more source

A pyrrolidine-based specific inhibitor of cytosolic phospholipase A2α blocks arachidonic acid release in a variety of mammalian cells

, 2001
Farideh Ghomashchi, Allison Stewart, Ying Hefner, Sasanka Ramanadham, John Turk, Christina C. Leslie, Michael H. Gelb   +6 more
openalex   +1 more source

Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction

Fundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.
Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood, Marianne Lachaux, Najah Harouki, Matthieu Soulié, Lionel Nicol, Sylvanie Renet, Anaïs Dumesnil, Magali Vercauteren, Jeremy Bellien, Marc Iglarz, Vincent Richard, Paul Mulder   +11 more
wiley   +1 more source

Scalable Synthesis of Biologically Relevant Spirocyclic Pyrrolidines

ACS Omega, 2019
Kostiantyn P. Melnykov, Artem N. Artemenko, Bohdan O. Ivanenko, Yevhenii M. Sokolenko, Pavel S. Nosik, Eugeniy N. Ostapchuk, Oleksandr O. Grygorenko, Dmitriy M. Volochnyuk, Sergey V. Ryabukhin   +8 more
doaj   +1 more source