Results 141 to 150 of about 2,735 (188)

Percutaneous absorption of co-administered N-methyl-2-[14C]pyrrolidinone and 2-[14C]pyrrolidinone in the rat

Food and Chemical Toxicology, 1992
The percutaneous absorption has been investigated in rats of a mixture (3:2, w/w) of N-methyl-2-pyrrolidinone (NMP) and 2-pyrrolidinone (2-P), a combination intended for use as a vehicle in the formulation of an antimycotic drug to enhance skin penetration on dermal application, following co-administration of the two 14C-radiolabelled compounds by the ...
I, Midgley, A J, Hood, L F, Chasseaud, C J, Brindley, S, Baughman, G, Allan   +5 more
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Aneuploidy induction in Saccharomyces cerevisiae by two solvent compounds, 1‐methyl‐2‐pyrrolidinone and 2‐pyrrolidinone

Environmental and Molecular Mutagenesis, 1988
AbstractA number of solvent compounds that were tested in Saccharomyces cerevisiae were potent inducers of aneuploidy, although they did not induce any other genetic effects. As an extention of these earlier findings, 1‐methyl‐2‐pyrrolidinone was tested and was found to induce aneuploidy.
V W, Mayer, C J, Goin, R E, Taylor-Mayer
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Studies on Pyrrolidinones: Chemistry of Dimethoxytriazines

Synthesis, 2013
The synthesis of dimethoxytriazine-containing N-aryl substituted pyrrolidinones is realized for the first time. Three new modes of reactivity for these substrates possessing a 4,6-dimethoxy-1,3,5-triazine unit are discussed. Their treatment with acid leads to complete O-demethylation of the methoxy groups, while similar reaction in a basic medium leads
Alina Ghinet, Liliana Lucescu, Philippe Gautret, Souhila Oudir, Benoît Rigo, Dalila Belei, Elena Bîcu   +6 more
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ChemInform Abstract: Structural Analysis of Pyrrolidinones.

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fabrice Camus, Bernadette Norberg, Anne Legrand, Benoit Rigo, Francois Durant, Johan Wouters   +5 more
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Thermodynamic and spectroscopic properties of 2-pyrrolidinones. 2. Dielectric properties of 2-pyrrolidinone in binary mixtures

Journal of Solution Chemistry, 1990
Dielectric permittivities of 2-pyrrolidinone - acetone, -dimethyl sulfoxide,-2-propanol, -dichloromethane and -water systems were measured as a function of mole fraction over the whole composition range at 30 and 50°C. The excess dielectric permittivities are predominantly negative for all the mixtures and the excess molar polarizations are negative ...
P. Ruostesuo, P. Piril�-Honkanen
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Hypolipidemic Activity of Substituted 2-Pyrrolidinones in Rodents

Journal of Pharmaceutical Sciences, 1983
A series of substituted 2-pyrrolidinones was evaluated for hypolipidemic activity at 20 and 30 mg/kg/day in CF1 male mice. 4-Phenyl-5,5-dicarbethoxy-2-pyrrolidinone was the most potent compound at 30 mg/kg/day, reducing serum triglyceride levels 52% after 14 days of dosing and serum cholesterol levels 48% after 16 days of dosing.
G H, Cocolas, J M, Chapman, P J, Voorstad, I H, Hall   +3 more
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Structure of the 2-Pyrrolidinone Monohydrate

Zeitschrift für Naturforschung B, 1999
The X-ray crystal structure of the 1:1 adduct shows a complicated network of water and 2-pyrrolidinone molecules where the carbonyl oxygen atom of 2-pyrrolidinone forms hydrogen bonds with protons of two separate water molecules and the NH proton of the 2- pyrrolidinone molecule interacts with the oxygen atom of a third water molecule.
Päivi Pirilä, Ilpo Mutikainen, Jouni Pursiainen   +2 more
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Pyrrolidinones from the Ascomycete Fungus Albonectria rigidiuscula

Journal of Natural Products, 2009
The new pyrrolidinones, rigidiusculamides A-D (1-4), have been isolated from the crude extract of the ascomycete fungus Albonectria rigidiuscula. The structures of these compounds were elucidated primarily by NMR experiments. The absolute configuration of the 3,4-diol moieties in 1 and 4 was assigned using Snatzke's method.
Jian, Li, Shuchun, Liu, Shubin, Niu, Wenying, Zhuang, Yongsheng, Che   +4 more
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1-[2-(Vinylthio)ethyl]-2-pyrrolidinone

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1961
1. 1-[2-(Vinylthio)ethyl]-2-pyrrolidinone was synthesized. 2. New water-soluble polymers were prepared by the polymerization of 1 -[2-(vinylthio)ethyl]-2-pyrrolidinone and by its copolymerization with 1-vinyl-2-pyrrolidinone. 3.
M. F. Shostakovskii, F. P. Sidel'kovskaya, �. S. Shapiro, T. Ya. Ogibina   +3 more
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Co(II) complexes with 2-pyrrolidinone

Canadian Journal of Chemistry, 1969
For the known complexes CoL3X2 (X = Cl, Br, and L = 2-pyrrolidinone) a more detailed infrared study was made. Together with the electronic spectra this study indicates dissociation of CoL2X3 into CoL2X2 + L in chloroform and acetone solution. The conductivity measurements and the molecular weight determinations also support dissociation.
O. Bohunovsky, S. C. Jain, R. Rivest
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