Results 11 to 20 of about 1,535 (151)
Frontiers in Microbiology, 2023 Seven new compounds, including three isocoumarins (1–3), three pyrrolidinone derivatives (8–10), and one pentaene diacid (15), together with 13 known compounds, were isolated from the rice culture of the endophytic fungus Fusarium decemcellulare F25 ...
Ziwei Song +7 more
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Molecules, 2021 Ten benzoxazole clubbed 2-pyrrolidinones (11–20) as human monoacylglycerol lipase inhibitors were designed on the criteria fulfilling the structural requirements and on the basis of previously reported inhibitors.
Obaid Afzal +5 more
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Molecules, 2020 Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity.
Birutė Sapijanskaitė-Banevič +4 more
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β-Enamino Esters in Heterocyclic Synthesis: Synthesis of Pyrazolone and Pyridinone Derivatives
Molecules, 2010 An efficient and convenient synthesis of pyrrolidinones and pyridinones utilizing enamino esters as starting material has been described. The structures of the compounds obtained were confirmed by spectral and elemental analyses.
Abdellatif Mohamed Salaheldin +1 more
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Ultrasound-promoted synthesis of pyrrolidin-2-ones in aqueous medium
Orbital: The Electronic Journal of Chemistry, 2012 Pyrrolidin-2-ones have received considerable attention due to their activity in CNS as nootropic drugs. In parallel, the search for environmentally sustainable processes have been triggered the planning of actions related to organic synthesis.
Márcia Silvana Freire Franco +2 more
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Beilstein Journal of Organic Chemistry, 2013 The four-component reaction of 2-aminobenzothiazole, aromatic aldehydes, acetylenedicarboxylate and piperidine or pyrrolidine in ethanol afforded the functionalized 2-pyrrolidinones containing both benzothiazolyl and piperidinyl (or pyrrolidinyl) units ...
Hong Gao, Jing Sun, Chao-Guo Yan
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Synthesis of New Optically Active 2-Pyrrolidinones
Molecules, 2012 A new class of optically active 2-pyrrolidinones was synthesized, starting from S-pyroglutamic acid, a well known natural chiral synthon. The synthetic design followed led to the insertion of various substituents at positions 1 and 5 of the 2 ...
Thomas Mavromoustakos +2 more
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Pyrrolidinodiones in Enol-Ugi, Enol-Passerini, and Anomalous Enol-Passerini Condensations
Proceedings, 2019 In continuation of our recent research on the development of novel multicomponent reactions with isocyanides, we have used, for the first time, enols as the acid components in Ugi- and Passerini-type reactions. Thus, electron-poor pyrrolidinodiones react
Ana G. Neo, Carlos F. Marcos
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Synthesis of Spiroisoxazolines by 1,3-Dipolar Cycloaddition
Molecules, 1997 The cycloaddition of the chiral nitrile oxide 1 to 1-R-substituted 3,3-methylene-5,5-dimethyl-2-pyrrolidinones 2 (where R is H, n-butyl-, 1,1-dimethylethoxycarbonyl-, 1-methylethenyl- and acetyl-) proceeds regioselectively under the formation of ...
Peter Ertl +3 more
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Angewandte Chemie, EarlyView.Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar +8 more
wiley +2 more sources