Results 21 to 30 of about 2,735 (188)

The Concise Guide to PHARMACOLOGY 2015/16:Ligand-gated ion channels [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
Aldrich, R, Alexander, SPH, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Benson, HE, Biel, M, Birdsall, NJ, Boison, D, Brauner-Osborne, H, Broeer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J-J, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Davies, JA, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Faccenda, E, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hebert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kelly, E, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb-Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, Marrion, N, May, JM, Mazella, J, McArdle, CA, McDonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J-L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Pawson, AJ, Perez-Reyes, E, Pertwee, RG, Peters, JA, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sharman, JL, Sladek, FM, Southan, C, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M-J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J-P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, Zajac, J-M   +150 more
core   +9 more sources

Microwave-assisted synthesis of pyrrolidinone derivatives using 1,1’-butylenebis(3-sulfo-3H-imidazol-1-ium) chloride in ethylene glycol

Green Processing and Synthesis, 2019
The energy efficiency of the microwave-assisted synthesis of pyrrolidinones was demonstrated using catalytic loading of 1,1’-butylene-bis(3-sulfo-3H-imidazol-1-ium) chloride as a sulfonic acid functionalized ionic liquid in ethylene glycol as green ...
Khaligh Nader Ghaffari, Mihankhah Taraneh, Johan Mohd Rafie, Titinchi Salam J.J.   +3 more
doaj   +1 more source

The use of monosaccharides in metal-catalyzed coupling reactions [PDF]

, 2016
The addition of monosaccharides to metal-catalyzed coupling reactions can be beneficial in terms of decreasing the time required, chemical waste products and overall cost of the process. Monosaccharides are used in a number of different ways, including: (
Camp, Jason, Kyne, Sara
core   +1 more source

Probing binding and cellular activity of pyrrolidinone and piperidinone small molecules targeting the urokinase receptor [PDF]

, 2013
The urokinase receptor (uPAR) is a cell-surface protein that is part of an intricate web of transient and tight protein interactions that promote cancer cell invasion and metastasis. Here, we evaluate the binding and biological activity of a new class of
Knabe, William Eric, Li, Liwei, Liu, Degang, Mani, Timmy, Meroueh, Samy O., Oh, Kyungsoo, Wang, Fang, Zhou, Donghui   +7 more
core   +1 more source

Enantioselective Desymmetrization of Glutarimides Catalyzed by Oxazaborolidines Derived from cis-1-Amino-indan-2-ol [PDF]

, 2015
Enantioselective reductive desymmetrization of glutarimides has been achieved employing an oxazaborolidine catalyst derived from cis-1-amino-indan-2-ol.
Jones, S., Kutama, I.U.
core   +1 more source

A concise approach to functionalised, homochiral pyrrolidinones

Tetrahedron: Asymmetry, 1995
Abstract Acylation of O , N -acetal 1 gives excellent yields of the C-7 substituted products 2a,b . Alkylation of 2a under mild conditions gives high yields of the exo- 3 and endo- 4 substituted products in varying ratios, depending on the alkylating agent.
Bamford, M, Beard, M, Cherry, D, Moloney, M   +3 more
openaire   +1 more source

Recent trends in whole cell and isolated enzymes in enantioselective synthesis [PDF]

, 2011
Modern synthetic organic chemistry has experienced an enormous growth in biocatalytic methodologies; enzymatic transformations and whole cell bioconversions have become generally accepted synthetic tools for asymmetric synthesis.
Maguire, Anita R., Milner, Sinéad E.
core   +1 more source

Transition-Metal-Catalyzed Annulations Involving the Activation of C(sp3)−H Bonds [PDF]

, 2021
The selective functionalization of C(sp3)-H bonds using transitionmetal catalysis is among the more attractive transformations of modern synthetic chemistry.
Font Molíns, Marc, Gulías Costa, Moisés, Mascareñas Cid, José Luis   +2 more
core   +1 more source

Ultrafast, High‐Capacity Uranium Harvesting From Seawater via a Hierarchically Porous Polymer Electrode

Advanced Science, EarlyView.
A hierarchically porous AOPIM‐CNT electrode enables uranium harvesting from seawater via adsorption‐promoted electrodeposition. Rapid diffusion and selective adsorption are coupled with electrochemical crystallization and spontaneous detachment, creating a self‐refreshing process that sustains high‐capacity, continuous extraction from ultradilute ...
Zejun Song, Zhenggong Wang, Lele Guo, Zhining Wang, Keming Wan, Ting Zhang, Wangxi Fang, Jian Jin   +7 more
wiley   +1 more source

Palladium-Catalyzed Construction of Quaternary Stereocenters by Enantioselective Arylation of γ-Lactams with Aryl Chlorides and Bromides [PDF]

, 2019
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two sets of conditions were developed for this transformation, allowing for the use of either aryl chlorides or bromides as electrophiles.
Bachman, Shoshana, Geibel, Irina, Hayashi, Masaki, Jette, Carina I., Morgan, Jeremy B., Sakurai, Shunya, Shimizu, Hideki, Stoltz, Brian M.   +7 more
core   +1 more source