Results 71 to 80 of about 2,138 (143)

A versatile approach to cis-5-substituted 4-hydroxy-2-pyrrolidinones: asymmetric synthesis of angiogenesis inhibitor streptopyrrolidine

, 2009
A concise, flexible, and highly diastereoselective approach to cis-5-alkyl-4-hydroxy-2-pyrrolidinones 1 is described. The key step is an ammonium acetate-assisted catalytic hydrogenation of the enamides 9, derived in two steps from malimides 6a,b as we ...
Yuan, Hong-Qiu, Xiang, Shao-Hua, Huang, Pei-Qiang, 黄培强, Hong-Qiu Yuan, Pei-Qiang Huang, Shao-Hua Xiang   +6 more
core   +1 more source

Complementary stereocontrolled approaches to 2-pyrrolidinones bearing a vicinal amino diol subunit with three continuous chiral centers: A formal asymmetric synthesis of (-)-detoxinine

, 2007
[GRAPHICS] We report herein two stereocomplementary approaches to erythro/trans and threo/cis vicinal amino diol subunits containing 2-pyrrolidinones (9 and 10) starting from the known enamides 7, easily available from malimides.
Liu, Wen-Jun, Zhou, Xiang, Huang, Pei-Qiang, 黄培强, Ye, Jian-Liang   +4 more
core   +1 more source

Relay Organophotoredox/N‑Heterocyclic Carbene Catalysis-Enabled Asymmetric Synthesis of Dibenzoxazepine-Fused Pyrrolidinones

An unprecedented highly stereoselective synthesis of pyrrolo­[1,2-d]­[1,4]­oxazepin-3­(2H)-ones has been accomplished via photoredox/N-heterocyclic carbene (NHC) relay catalysis.
Yaseen Hussain (8567226), Deepak Sharma (131639), Tamanna (12431111), Pankaj Chauhan (559259)   +3 more
core   +1 more source

Synthesis and structural characterization of products condensation 4-carboxy-1-(4-styrylcarbonylphenyl)-2-pyrrolidinones with hydrazines

ARKIVOC, 2007
Ausra Voskiene, Vytautas Mickevicius, Gema Mikulskiene   +2 more
doaj   +1 more source

Preparation of 1,5-Disubstituted 2-Pyrrolidinones Via α-Amidoalkylation

, 1997
在酸催化条件下，1-苄基-5-苯砜基-2-吡咯烷酮与三类亲核试剂反应以良好的产率得到相应的酰胺α-烷基化产物5-取代-1-苄基-2-吡咯烷酮Acid\ catalyzed\ α-amidoalkylation\ of\ 1-benzyl-5-phenylsulFonyl-2-pyrrolidinone with three type of nucleophile led the Formation of the corresponding 5-substituted-1-benzyl-2 ...
郑洪, 黄培强, 陈忠
core  

Increased Libido Following Brivaracetam Initiation: A Case Report of Temporal Lobe Epilepsy. [PDF]

Neuropsychopharmacol Rep
Horinouchi T, Matsuyama T, Mito M, Nakamura Y, Kato TA.   +4 more
europepmc   +1 more source

Halogenated Reagents in the Ugi Reaction: From Rearrangement Reactions to Ketal Synthesis. [PDF]

ACS Omega
González-Saiz B, Cámara-Herrero C, Díaz-Cabrera S, Carreira-Barral I, Quesada R, García-Valverde M.   +5 more
europepmc   +1 more source

Further Insights Into the Metabolism of LGD-4033 in Human Urine. Part 1. Structure Elucidation of Additional Important Metabolites. [PDF]

Drug Test Anal
Angelis YS, Sakellariou P, Thevis M, Thomas A, Petrou M, Pitsinos EN.   +5 more
europepmc   +1 more source

Nickel-Catalyzed Cyclization/Carbonylation Reaction of N-Allylbromoacetamides with Arylboronic Acids toward 2-Pyrrolidinones. [PDF]

Org Lett
Ma H, Hou CY, Zhao R, Qi X, Wu XF.
europepmc   +1 more source

Durable response to vebreltinib in heavily pretreated MET-amplified intrahepatic cholangiocarcinoma: a case report. [PDF]

Oncologist
Hang Y, Bai L, Hsu H, Chen Y, Wang F, Xu W, Zhen X, Wang Z, Li Y, Qian J.   +9 more
europepmc   +1 more source