Results 51 to 60 of about 2,072 (186)

Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.

, 2006
The synthesis and preliminary structure-activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-
Wolff, Karen, Yang, Kunyong, Anaclerio, Beth, Caldwell, Jeremy, Karanewsky, Donald, Wu, Baogen, Kuhen, Kelli, Ngoc Nguyen, Truc, Bieza, Kimberly, He, Yun, Ellis, David, He, Xiaohui, Yin, Hong   +12 more
core  

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, Volume 38, Issue 33, 12 June 2026.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Tandem Visible Light-Mediated Radical Cyclization–Divinylcyclopropane Rearrangement to Tricyclic Pyrrolidinones

, 2016
Visible light promoted single electron reduction of bromocyclopropyl cyclization scaffolds enabled by photoredox catalysis initiates a novel tandem radical cyclization/sigmatropic rearrangement to generate tricyclic pyrrolidinones having considerable ...
Joseph W. Tucker (1489075), Corey R. J. Stephenson (1328196)   +1 more
core   +1 more source

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

Bioactive Composition and Antioxidant and Glycemic‐Regulating Properties of Basella alba L. Leaf, Fruit, and Stem: GC–MS, FTIR, In Vitro and In Silico Insights

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The bioactive composition, antioxidant capacity, and glycemic‐regulating properties of Basella alba L. leaf, fruit, and stem were comparatively analyzed using gas chromatography–mass spectrometry (GC–MS), Fourier‐transform infrared spectroscopy (FTIR), in vitro assays, and molecular docking analyses.
Shorna Das, Satyajit Roy Rony, Bidduth Kumar Sarkar, Sukalyan Kumar Kundu, Pradip Debnath   +4 more
wiley   +1 more source

PCL/Chitosan/Bioglass Hybrid Composite Shape Memory Scaffolds With Accelerated Degradation and Enhanced Bioactivity

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
Hybrid composite shape memory scaffolds were developed for potential craniomaxillofacial bone defect repair. These scaffolds exhibit accelerated degradation and induce rapid, robust hydroxyapatite mineralization in 1X simulated body fluid (SBF). ABSTRACT “Self‐fitting” shape memory polymer (SMP) scaffolds based on cross‐linked poly(ε‐caprolactone ...
Damion T. Dixon, Darian K. Kanu, Melissa A. Grunlan   +2 more
wiley   +1 more source

Ferromagnetic Cobalt Oxide With Structural Distortion and Oxidation State Changes for Hydrogen Sulfide Gas Detection

Small, Volume 22, Issue 32, 8 June 2026.
High H2S gas sensitivity was improved by electrochemically engineering Co3O4/CoO heterostructures with oxygen vacancies and aligning nanosized particles via magnetic‐field‐assisted deposition. This alignment enhanced gas diffusion and electron transport, reducing base resistance. The resulting sensor exhibited high selectivity and a strong response (Rg/
Shin Joon Kang, Chang Yoon Kim, Min Chan Kim, Sunhyeong Kwon, Joon‐Shik Park, Hyung Mo Jeong   +5 more
wiley   +1 more source

Infrared Study of Solvent-Solute Interactions of 1-Substituted 2-Pyrrolidinones and Related Compounds [PDF]

, 1995
The wavenumbers of the carbonyl stretching vibrations of 2-pyrrolidinone (P), 1-methyl-2-pyrrolidinone (MP), 1-isopropyl-2-pyrrolidinone (IPP), 1-(2-hydroxyethyl)-2-pyrrolidinone (HEP), 2-oxobenzothiazole (OBT), and 3-octyl-2-oxobenzothiazole (OOBT) were
Engberts, J.B.F.N.,, Engberts, J.B.F.N., Perjéssy, A.,, J. B. F. N. Engberts, A. Perjéssy, Perjéssy, A.   +5 more
core   +1 more source

Thermally Bistable Stiff Stilbene Photoswitches and Polymer Applications

The Chemical Record, Volume 26, Issue 6, June 2026.
Thermally stable photoswitches offer new opportunities for controlling polymer structures and functions under nonequilibrium conditions. This Personal Account highlights stiff stilbene (SS) and sterically hindered stiff stilbene (HSS) photoswitches, which combine large structural changes with exceptional thermal bistability.
Keiichi Imato
wiley   +1 more source

An alternative stereoselective synthesis of protected trans-5-alkyl-4-hydroxy-2-pyrrolidinones

, 2007
A flexible approach to protected trans-5-alkyl-4-hydroxy-2-pyrrolidinones was described. The key step involved the alpha-amidoalkylation of benzenesulfone derived from (S)-malic acid, with organozinc reagents generated in situ from Grignard reagents and ...
Chen, AQ, Tang, X, Huang, PQ, 陈安奇, 黄培强   +4 more
core   +1 more source