Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
Bioenergetic Signatures of DLD Deficiency: Dissecting PDHc- and α-KGDHc-Linked Defects. [PDF]
Haham Zarbib Y +12 more
europepmc +1 more source
The multidimensional regulation roles and mechanisms of calcium in fruit quality
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang +6 more
wiley +1 more source
Impact of COVID-19 infection in patients with inherited metabolic diseases: a National Multicenter Study from the French IMDs Healthcare Network for Rare Diseases. [PDF]
Douillard C +24 more
europepmc +1 more source
Antigenically dominant proteins within the human liver mitochondrial proteome identified by monoclonal antibodies [PDF]
FuChu He +13 more
core +1 more source
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng +12 more
wiley +1 more source
Mitochondrial Dysfunction in Propionic Acidemia: A Case-Report and Review of the Literature. [PDF]
Walther BK +5 more
europepmc +1 more source
Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap +3 more
wiley +1 more source
Case Report: Neonatal heart failure: a rare presentation of congenital left ventricular aneurysm. [PDF]
Alsuayyid A +3 more
europepmc +1 more source
The effects of vitamin B in depression [PDF]
Apostolopoulos, Vasso +2 more
core +1 more source

