Results 121 to 130 of about 22,061 (226)

Protein STM3547 From Salmonella typhimurium Is a Phosphofructose Kinase B‐Type Enzyme With Ribose Kinase Activity

Molecular Microbiology, EarlyView.
The metabolism of ribose starts with the phosphorylation of its 5′ hydroxyl group. Salmonella typhimurium has two kinases that perform this function, namely ribose rinase (RbsK) and deoxyribose kinase (DeoK). Here we report a new ribose kinase that we named RikA. The illustration was partially created in BioRender.
Regan D. McCormick, Aatif A. Jabbar, Jorge C. Escalante‐Semerena   +2 more
wiley   +1 more source

Photoreceptor deletion of pyruvate dehydrogenase E1 subunit α1 induces retinal degeneration and reprograms retinal metabolism. [PDF]

Mol Metab
Ma H, York LR, Li S, Gagnon G, Zou J, Yu H, Yang J, Le Y, Eminhizer M, Mascari I, Du J, Ding XQ.   +11 more
europepmc   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, EarlyView.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Expanding the MRPS34 Genotype–Phenotype Correlation: Two Novel Cases and a Cohort Review [PDF]

JIMD Rep
ABSTRACT MRPS34 encodes a mitoribosomal protein essential for mitochondrial translation. Biallelic pathogenic variants in MRPS34 cause Combined Oxidative Phosphorylation Deficiency 32 (COXPD32), a rare mitochondrial disorder within the Leigh syndrome spectrum (LSS), ranging from fatal in infancy to adult survival.
Lundquist A, Parikh S, Hansen T, Wibrand F, Østergaard E.   +4 more
europepmc   +2 more sources

Regulation of gluconeogenesis in type 2 diabetes mellitus: An investigation of the role of corticosteroids?

, 2012
PhDType 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormones and metabolites. Over expression of key gluconeogenic enzymes, such as PEPCK, cause features of T2DM including obesity and insulin resistance ...
Nayuni, Nanda Kishore Babu
core  

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, EarlyView.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Bioenergetic Signatures of DLD Deficiency: Dissecting PDHc- and α-KGDHc-Linked Defects. [PDF]

Antioxidants (Basel)
Haham Zarbib Y, Huri Ohev-Shalom S, Lyskov SK, Mazor Y, Anekstein-Spigel M, Shalva N, Spiegel R, Staretz-Chacham O, Manor J, Saada A, Rock R, Anikster Y, Yardeni T.   +12 more
europepmc   +1 more source

Models of neurodegenerative mitochondrial disease

, 2011
Mitochondrial diseases affect the core energy generating pathways and can result in significant cognitive impairment and neurodegeneration. The mechanisms underlying the neurological and pathological consequences of mitochondrial disease are not ...
Sleven, Hannah
core  

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn, Fabian B. Haas, Benjamin G. Chavez, Bernd H. Dreyer, Erik V. Reiss, Anne Ziplys, Heiko Weichert, Saskia Hiltemann, José M. Ugalde, Andreas J. Meyer, John C. D'Auria, Stefan A. Rensing, Jos H. M. Schippers   +12 more
wiley   +1 more source