Results 151 to 160 of about 47,907 (257)

Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders

open access: yesExperimental Physiology, EarlyView.
Abstract Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex‐specific manifestations of ASD. This study aims to examine ASD‐like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
Süeda Tunçak   +3 more
wiley   +1 more source

Modelling the effect of varying metabolic rate and cardiac output on estimated tissue and blood O2 and CO2 levels in an extreme deep‐diver, the goose‐beaked whale (Ziphius cavirostris)

open access: yesExperimental Physiology, EarlyView.
Abstract High‐resolution movement data from Cuvier's beaked, or goose‐beaked whale (Ziphius cavirostris, hereafter Ziphius, n = 8) tag deployments (4.1–19.2 days) were used to estimate blood and tissue O2 and CO2 levels. Acceleration and magnetometry data were used to estimate the locomotion cost (LC) from the relationship between activity and the O2 ...
Andreas Fahlman   +8 more
wiley   +1 more source

When rehabilitation is not enough, how targeting metabolism can overcome the limited plasticity of skeletal muscle after traumatic injury

open access: yesExperimental Physiology, EarlyView.
Abstract There is a category of large‐scale neuromusculoskeletal injuries that result in long‐term functional disabilities, and one such injury is volumetric muscle loss (VML) injury. In addition to the clinical outcomes related to long‐term dysfunction, co‐morbidities and reduced mobility and physical activity, this review addresses several ...
Sarah M. Greising, Jarrod A. Call
wiley   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

CRABS-ROC, A respirometry protocol for overcoming substrate limitations, reveals excess brain mitochondrial Complex I capacity. [PDF]

open access: yesFree Radic Biol Med
Zhang N   +5 more
europepmc   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

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