An Essential Role of Glu-243 and His-239 in the Phosphotransfer Reaction Catalyzed by Pyruvate Dehydrogenase Kinase [PDF]
, 2001 Alina Tuganova +2 more
openalex +1 more source
Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu +3 more
wiley +1 more source
Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression. [PDF]
Oncol Rep, 2023 Yang ES +8 more
europepmc +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra +3 more
wiley +1 more source
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation. [PDF]
Cell Mol Gastroenterol Hepatol, 2023 Lee H +12 more
europepmc +1 more source
Regulation of Pyruvate Dehydrogenase Kinase Expression by Peroxisome Proliferator–Activated Receptor-α Ligands, Glucocorticoids, and Insulin [PDF]
, 2002 Boli Huang +3 more
openalex +1 more source
Insect Science, EarlyView.Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido +4 more
wiley +1 more source
Biogenesis of Organelles and Membrane Proteins. [PDF]
, 1988 Harmey, Matthew A. +3 more
core +1 more source
Pyruvate dehydrogenase kinase 1 promotes neuronal apoptosis upon Japanese encephalitis virus infection. [PDF]
IBRO Neurosci Rep, 2022 Chakraborty S, Sen E, Basu A.
europepmc +1 more source
Evaluation of the role of peroxisome-proliferator-activated receptor α in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism [PDF]
, 2002 Mark J. Holness +5 more
openalex +1 more source