Results 61 to 70 of about 24,261 (292)

Determining enantiomeric excess using indicator-displacement assays [PDF]

, 2005
The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically.
Eric V. Anslyn, J. Frantz Folmer-Andersen, Lei Zhu   +2 more
core   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

Effects of fermentation time and pH on soursop (Annona muricata) vinegar production towards its chemical compositions [PDF]

, 2017
Vinegar is a liquid product that undergoes both alcoholic and acetous fermentation of sugar (carbohydrate) sources. Soursop (Annona muricata) is easily available in Malaysia throughout the year. However, it is also highly perishable and has a short shelf-
Azwan Mat Lazim,, Chin, Wai Ho, Lim, Seng Joe, Shazrul Fazry,, Umi Kalsum Hj Hussain Zaki,   +4 more
core   +1 more source

Oxaloacetate as a Holy Grail Adjunctive Treatment in Gliomas: A Revisit to Metabolic Pathway. [PDF]

Cureus, 2023
Samad A, Samant R, Venkateshwara Rao K, Bhargava V, Sadique SI, Yadav R.   +5 more
europepmc   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

Advanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen, James Davies, Aditya Ashok, Trung Thien Hoang, Anahid Ehteda, Tran Bach Dang, Emanuele Nicotra, Hien A. Tran, Bibhu Sharma, Kefan Zhu, Phuoc Thien Phan, Adrienne Ji, Jingjing Wan, Jelena Rnjak‐Kovacina, Orazio Vittorio, Hoang‐Phuong Phan, Nigel Hamilton Lovell, Thanh Nho Do   +17 more
wiley   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Algae Biofuel Triacylglyceride Transesterification Optimization [PDF]

, 2018
Algae biofuels may hold the key to solving the problem of fossil fuel consumption by being comparable in content, renewable, and carbon-neutral. Many biofuel researchers and corporations have undertaken to increase the production rate or capacity of ...
Ferenczy, Erik
core   +1 more source

48XXYY Syndrome in an Adult with Type 2 Diabetes Mellitus, Unilateral Renal Aplasia, and Pigmentary Retinitis [PDF]

, 2010
A 45-year-old male was referred for diabetes mellitus. Clinical examination found a family history of multiple precocious deaths, strong consanguinity, personal history of seizures during childhood, small testicles, small penis, sparse body hair, long ...
Alaya, Wafa, Jerbi, Saida, Kamoun, Mahdi, Mkaouar, Emna, Sfar, Mohamed Habib, Younes, Samia, Zantour, Baha   +6 more
core   +3 more sources

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source