Results 71 to 80 of about 25,295 (321)

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

open access: yesAdvanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon   +6 more
wiley   +1 more source

Simulation and optimization of simultaneous fermentation and separation of butanol using pervaporation technique [PDF]

open access: yes, 2007
Product inhibition continues to be one of the major problems impeding the continuous production of butanol by fermentation process. Although many techniques are available which could sort out the fore mentioned problem, pervaporation continues to be the ...
Kottukappally, Aby J   +1 more
core  

Oxaloacetate as a Holy Grail Adjunctive Treatment in Gliomas: A Revisit to Metabolic Pathway. [PDF]

open access: yesCureus, 2023
Samad A   +5 more
europepmc   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann   +9 more
wiley   +1 more source

The influence of volatile compounds of the flavour of raw, boiled and baked potatoes: Impact of agricultural measures on the volatile components [PDF]

open access: yes, 2009
In dem Beitrag werden die Entstehungswege flüchtiger Verbindungen in rohen, gekochten und gebackenen Kartoffeln und deren Bedeutung für das Kartoffelaroma aufgezeigt.
Böhm, Herwart, Dresow, Jana F.
core  

Pyruvate kinase deficiency and severe congenital hemolytic anemia in a double heterozygous patient with paternal transmission of an early germ‐line de novo mutation [PDF]

open access: bronze, 2015
María del Mar Mañú‐Pereira   +9 more
openalex   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

Blood vessel tortuosity selects against evolution of aggressive tumor cells in confined tissue environments: A modeling approach [PDF]

open access: yes, 2017
Cancer is a disease of cellular regulation, often initiated by genetic mutation within cells, and leading to a heterogeneous cell population within tissues.
Szabo, A
core  

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