Results 51 to 60 of about 6,424,880 (277)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

High-Q-Factor Silica-Based Racetrack Microring Resonators

Photonics, 2021
In this paper, ultrahigh-Q factor racetrack microring resonators (MRRs) are demonstrated based on silica planar lightwave circuits (PLCs) platform. A loaded ultrahigh-Q factor Qload of 1.83 × 106 is obtained.
Yue-Xin Yin, Xiao-Jie Yin, Xiao-Pei Zhang, Guan-Wen Yan, Yue Wang, Yuan-Da Wu, Jun-Ming An, Liang-Liang Wang, Da-Ming Zhang   +8 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha [PDF]

, 2002
Heparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction.
Mardon, Helen J., Yoo, Hyung-J, Katya Chobotova, Barlow, David, Helen J. Mardon, Carver, J, Chobotova, K, Muchmore, ME, William J. Gullick, Muchmore, Mary-Elizabeth, Chobotova, Katya, Janet Carver, Yoo, HJ, Hyung-J Yoo, David H. Barlow, Manek, Sanjiv, Sanjiv Manek, Manek, S, Barlow, DH, Mary-Elizabeth Muchmore, Gullick, WJ, Gullick, William J., Carver, Janet, Mardon, HJ   +23 more
core   +1 more source

A Comparative Study of Insulators on Magnetic Properties of Sendust Based Nanocomposite Powder Cores [PDF]

Journal of Optoelectronical Nanostructures, 2018
In this study, Sendust (Fe85Si9.6Al5.4) nanostructure alloy was prepared bymechanical alloying and was characterized by X-ray diffraction.
Maryam Amoohadi, Morteza Mozaffari, Abdolrasoul Gharaati, Mohammad Rezazadeh   +3 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Live Cell Therapy as Potential Risk Factor for Q Fever

Emerging Infectious Diseases, 2017
During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans.
Maja George, Andreas Reich, Klaus Cussler, Herrmann Jehl, Florian Burckhardt   +4 more
doaj   +1 more source

A 5.86 Million Quality Factor Cylindrical Resonator with Improved Structural Design Based on Thermoelastic Dissipation Analysis

Sensors, 2020
The cylindrical resonator is the core component of cylindrical resonator gyroscopes (CRGs). The quality factor (Q factor) of the resonator is one crucial parameter that determines the performance of the gyroscope. In this paper, the finite element method
Libin Zeng, Yiming Luo, Yao Pan, Yonglei Jia, Jianping Liu, Zhongqi Tan, Kaiyong Yang, Hui Luo   +7 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Interaction between coaxial dielectric disks enhances the Q-factor

, 2019
We study the behavior of resonant modes under variation of the distance between two coaxial dielectric disks and show an avoided crossing of resonances because of interaction between the disks.
A. F. Sadreev (17492211), K. N. Pichugin (17507649)   +1 more
core   +1 more source