Results 31 to 40 of about 1,187,227 (316)

Analysis of simultaneous Q-switching and frequency doubling in KTP

, 1997
Simultaneous Q-switching and second harmonic generation in KTP is analysed numerically. In this mode of operation, the phase matching condition for second harmonic generation and the half-wave voltage for Q-switching are interrelated. In this paper, this
Yao, J. Q., Sun, X. W., Kwok, H. S.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Submicrosecond Q-Switching Er-Doped All-Fiber Ring Laser Based on Black Phosphorus

Advances in Condensed Matter Physics, 2017
Black phosphorus (BP), a new two-dimensional (2D) material, has been deeply developed for extensive applications in electronics and optoelectronics due to its similar physical structure to graphene and thickness dependent direct band gap.
Yao Cai, Yanliang He, Xiaoke Zhang, Rui Jiang, Chenliang Su, Ying Li   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Buildup and Real-Time Control of Spatiotemporal Nonlinear Dynamics

Ultrafast Science
Ultrafast multimode fiber lasers enable the high-dimensional control of pulses, which can generate spatiotemporal mode-locking with high peak power and multimode Q-switching with large pulse energy.
Jingxuan Sun, Gang Wang, Congyu Zhang, Wenhao Lyu, Yunyu Lyu, Bo Fu   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Q-switching instability in a mode-locked semiconductor laser

, 2006
We suggest semianalytic estimates for the Q-switching instability boundary of the continuous-wave (cw) mode-locking regime domain for a ring-cavity semiconductor laser.
Bandelow, Uwe, Vladimirov, Andrei G., Bernd Hüttl, Ronald Kaiser, Uwe Bandelow, Hüttl, Bernd, Rachinskii, Dmitrii, Andrei Vladimirov, Kaiser, Ronald, Dmitrii Rachinskii   +9 more
core   +1 more source

Investigation of Nonlinear Optical Modulation Characteristics of MXene VCrC for Pulsed Lasers

Molecules, 2022
We report the surface morphology and the nonlinear absorption characteristics of MXene VCrC nanosheets prepared by the liquid-phase exfoliation method.
Yao Meng, Yizhou Liu, Tao Li, Tianli Feng, Jiacheng Huang, Zheng Ni, Wenchao Qiao   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source