Results 81 to 90 of about 936,931 (309)

Chemical profiling by UHPLC-Q-TOF-HRESI-MS/MS and antibacterial properties of Entada abyssinica (Fabaceae) constituents

open access: yes, 2023
A rapid untargeted UHPLC-Q-TOF-ESI-MS/MS-Based metabolomic profiling of the medicinal plant Entada abyssinica was performed. A total of 18 metabolites were detected, of which 10 could not be identified.
Abel J. G. Yaya (17410873)   +8 more
core   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

open access: yesAdvanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li   +22 more
wiley   +1 more source

Differential metabolites identified using UHPLC-LTQ-IT-MS/MS and UPLC-Q-TOF-MS in before/after bioconversion of Acer.

open access: yes, 2018
Differential metabolites identified using UHPLC-LTQ-IT-MS/MS and UPLC-Q-TOF-MS in before/after bioconversion of Acer.
Dong Ho Suh (2155582)   +5 more
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Metabolomics fingerprinting of Egyptian calendula (Calendula officinalis L.) essential oil and absolute by direct infusion into rapid evaporative ionization mass spectrometry

open access: yesGreen Analytical Chemistry
The present research is intended to provide a rapid and thorough method for the detection and characterization of the metabolites present in Calendula officinalis L.
Domenica Mangraviti   +6 more
doaj   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Data from RPLC- and HILIC-ESI (±)-Q-TOF MS.

open access: yes, 2018
Data from RPLC- and HILIC-ESI (±)-Q-TOF MS.
Tieshuai Du (5749028)   +7 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Q-TOF MS data for the evaluation of ioversol adsorption by desalination tube.

open access: yes, 2022
Q-TOF MS data for the evaluation of ioversol adsorption by desalination tube.
Shingo Ema (12800093)   +12 more
core   +1 more source

A Systematic Study of the Metabolites of Dietary Acacetin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS Analysis

open access: yes, 2019
Acacetin, a dietary component, is abundant in acacia honey and has superior anticancer activities. To date, no research on the metabolism of acacetin has been reported.
Lantong Zhang (4007096)   +11 more
core   +2 more sources

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