Results 11 to 20 of about 13,598 (189)

Unraveling the Role of Azobenzene-Based Photoswitchable Lipids in Controlling Innate Immune Response. [PDF]

Chemistry
We have shown the effect of photoswitchable azobenzene‐based lipids on the TIM‐3‐mediated activation of the immune system. Abstract The control of the activation of the innate immune response, notably by using suitable visible light sources, may lead the way to the development of phototimmunotherapeutic strategies.
Delova A, Makhloutah A, Bernhard Y, Pasc A, Monari A.   +4 more
europepmc   +2 more sources

Features of HLA-A*02 in Identifying Eligible Patients for Tecelra TCR-T Therapy. [PDF]

Cancer Sci
This study investigates the molecular mechanisms behind HLA‐A*02 subtypes' differential responses to Tecelra, a TCR‐engineered T‐cell therapy targeting MAGE‐A4. Using computational tools, the study identifies specific HLA‐A*02 alleles, such as HLA‐A*02:07, HLA‐A*02:05, and others, with low affinity for the GV10 peptide or a risk of inducing ...
Yang M, Zhong P, Jiao H, Wei P.
europepmc   +2 more sources

Should the Workload of Combining Clinical Practice With Data Collection be Considered: A Survey of Physicians With Data Collection Experience. [PDF]

J Evid Based Med
ABSTRACT Aim To survey the physician's attention to the workload of combining clinical practice with Traditional Chinese Medicine (TCM) data collection. Background With the development of artificial intelligence technology in the medical field, the task of collecting diverse clinical data in TCM has increased.
Zhang X, Jiang Y, Guan Z, Zhao M, Hu M, Xu Q, Wang W, Gao W, Qiu R, Li M, Yang B, Zhou L, Liu Z, Li Z, Xiang Y, Zhao J, Wang Z, Lou X, Guo S, Dai G, Bian Z, Wang H, Zhao C, Shang H.   +23 more
europepmc   +2 more sources

Localization of a Gene (MCUL1) for Multiple Cutaneous Leiomyomata and Uterine Fibroids to Chromosome 1q42.3-q43 [PDF]

The American Journal of Human Genetics, 2001
Dominant transmission of multiple uterine and cutaneous smooth-muscle tumors is seen in the disorder multiple leiomyomatosis (ML). We undertook a genomewide screen of 11 families segregating ML and found evidence for linkage to chromosome 1q42.3-q43 (maximum multipoint LOD score 5.40). Haplotype construction and analysis of recombinations permitted the
Alam, N A, Bevan, S, Churchman, M, Barclay, E, Barker, K, Jaeger, E E M, Nelson, H M, Healy, E, Pembroke, A C, Friedmann, P S, Dalziel, K, Calonje, E, Anderson, J, August, P J, Davies, M G, Felix, R, Munro, C S, Murdoch, M, Rendall, J, Kennedy, S, Leigh, I M, Kelsell, D P, Tomlinson, I P M, Houlston, R S   +23 more
openaire   +5 more sources

Real-world lecanemab adoption in Japan 1 year after launch: Insights from 311 specialists on infrastructure and reimbursement barriers. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Lecanemab was approved for early Alzheimer's disease in Japan, with ≈ 6000 patients treated in the first year post approval. This study explores real‐world practices, challenges, and potential solutions. METHODS We conducted an anonymized online survey of clinical specialists authorized to prescribe lecanemab, obtaining responses ...
Sato K, Niimi Y, Ihara R, Iwata A, Nemoto K, Arai T, Higashi S, Igarashi A, Kasuga K, Akiyama H, Awata S, Ikeda M, Iwatsubo T.   +12 more
europepmc   +2 more sources

Targeted next-generation sequencing identifies the disruption of the SHANK3 and RYR2 genes in a patient carrying a de novo t(1;22)(q43;q13.3) associated with signs of Phelan-McDermid syndrome [PDF]

Molecular Cytogenetics, 2020
Abstract Background It has been known for more than 30 years that balanced translocations, especially if de novo, can associate with congenital malformations and / or neurodevelopmental disorders, following the disruption of a disease gene or its cis-regulatory elements at one or both breakpoints.
Bonaglia M. C., Bertuzzo S., Ciaschini A. M., Discepoli G., Castiglia L., Romaniello R., Zuffardi O., Fichera M., Fichera M.   +8 more
openaire   +4 more sources

Panel Estimation of the Environmental Kuznets Curve for CO2 Emissions and Ecological Footprint: Environmental Sustainability in Developing Countries

Folia Oeconomica Stetinensia, 2022
Research background: The relationship between the economy and the environment is one of the most frequently encountered issues recently. Today the issue of environmental sustainability is one of the problems faced by countries.
Konya Sevilay
doaj   +1 more source

The Development of a Valid and Reliable Questionnaire to Measure Menstrual Cycle and Hormonal Contraceptive Knowledge Among Athletes and Sports Performance Support Staff. [PDF]

Scand J Med Sci Sports
ABSTRACT This study aimed to develop the first valid questionnaire to assess menstrual cycle (MC) and hormonal contraceptive (HC) knowledge in athletes and sports performance support staff. Questions were developed following a literature review and four knowledge domains were identified: (1) Normal MC Function, (2) MC Dysfunction, (3) Oral ...
Larsen B, Greet E, Bird SP, Quinn K, McNamara A, Osborne JO.   +5 more
europepmc   +2 more sources

The Bound State S-Matrix for AdS5 x S5 Superstring [PDF]

, 2009
We determine the S-matrix that describes scattering of arbitrary bound states in the light-cone string theory in AdS5 x S5. The corresponding construction relies on the Yangian symmetry and the superspace formalism for the bound state representations ...
A. Torrielli, Ambjorn, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Arutyunov, Bajnok, Bargheer, Beccaria, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Chen, de Leeuw, de Leeuw, de Leeuw, Dorey, Fiamberti, Frolov, G. Arutyunov, Gomez, Gromov, Gromov, Gromov, Hatsuda, Heckenberger, Heller, Hofman, Janik, Janik, Kazakov, Khoroshkin, Klose, Klose, Luscher, M. de Leeuw, Martins, Matsumoto, Matsumoto, Minahan, Minahan, Moriyama, Plefka, Roiban, Spill, Spill, Staudacher, Torrielli, Torrielli, Varshalovich, Zamolodchikov, Zwiebel   +62 more
core   +2 more sources

Justifiable Renewable Energy Usage from an Economic Angle

Acta Universitatis Sapientiae: Economics and Business, 2017
Worldwide, there is a huge demand for the application of renewable energy technologies mainly due to the current environmental problems that mostly originated from our fossil-based energy system.
Csuvár Ádám
doaj   +1 more source