Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives [PDF]
Background Chloride intracellular channel-1 (CLIC1) activity controls glioblastoma proliferation. Metformin exerts antitumor effects in glioblastoma stem cells (GSCs) inhibiting CLIC1 activity, but its low potency hampers its translation in clinical ...
Federica Barbieri +20 more
doaj +2 more sources
Should the Workload of Combining Clinical Practice With Data Collection be Considered: A Survey of Physicians With Data Collection Experience. [PDF]
ABSTRACT Aim To survey the physician's attention to the workload of combining clinical practice with Traditional Chinese Medicine (TCM) data collection. Background With the development of artificial intelligence technology in the medical field, the task of collecting diverse clinical data in TCM has increased.
Zhang X +23 more
europepmc +2 more sources
Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff. [PDF]
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Richards ND, Bekker HL, Howell SJ.
europepmc +2 more sources
Prevalence of congenital cryptorchidism in China: A nationwide population-based surveillance study, 2007-2021. [PDF]
Abstract Background Despite cryptorchidism being a common genital abnormality in male newborns with significant prevalence variations globally, there is a notable scarcity of epidemiological data on this condition in China. Objective This study aimed to delineate the prevalence pattern of cryptorchidism in Chinese population over the past 15 years ...
Li W +6 more
europepmc +2 more sources
Overstraining international climate finance: when conflicts of objectives threaten its success [PDF]
Purpose – Climate finance is regularly not only seen as a tool to efficiently combat global warming but also to solve development problems in the recipient countries and to support the attainment of sustainable development goals.
Wolfgang Buchholz, Dirk Rübbelke
doaj +1 more source
Taking water efficiency to the next level: digital tools to reduce non-revenue water
Efficiency optimization of urban water systems is a growing concern for water utilities worldwide. This case study aimed at evaluating the impact of using cloud-based tools on the reduction of both real (real-time network monitoring) and apparent water ...
J. Cassidy +6 more
doaj +1 more source
Sustainability of the rice-shrimp farming system in Mekong Delta, Vietnam: a climate adaptive model [PDF]
Purpose – Agricultural systems in Mekong Delta have transformed to cope with climate change. Various researches pointed out that integrated agriculture-aquaculture (IAA) farming systems (i.e., rice-shrimp, rice-fish…) emerged as potential climate ...
Huy Duc Dang
doaj +1 more source
Energy tokens as digital instruments of financial investment
The aim of the paper is to evaluate the investment attractiveness of selected energy tokens from the point of view of the effectiveness measures applied to ordinary financial instruments.
Marchewka-Bartkowiak Kamilla +1 more
doaj +1 more source
The Impact of the Polish Renewable Energy Sector on Employment
Subject and purpose of work: This study analyses employment in the renewable energy sector. The aim of this research was to explore the impact of obtaining energy from renewable sources on the labor market in Poland.
Gradziuk Piotr Lucjan
doaj +1 more source
The empirical link between education and consumption varies depending on contextual factors. Some studies have sought to find out the relationship between education and environmental concerns.
Mandarić Doroteja, Hunjet Anica
doaj +1 more source

