Results 51 to 60 of about 73,703 (332)

Molecular Surface Engineering of Sulfide Electrolytes with Enhanced Humidity Tolerance for Robust Lithium Metal All‐Solid‐State Batteries

Advanced Materials, EarlyView.
It is demonstrated that the electrochemical, interfacial, and humidity stability of halide‐doped sulfide electrolytes (LPSClBr) is significantly enhanced by an organic surface coating using octadecyl phosphonic acid (OPA) and its lithiated form (Li‐OPA). This single‐step strategy enables robust interfacial protection, supports lithium metal anodes, and
Laras Fadillah, Leonie Braks, Jihoon Oh, Mingliang Liu, Hanna Türk, Davide Tisi, Mounir Mensi, Michele Ceriotti, Jang Wook Choi, Ali Coskun   +9 more
wiley   +1 more source

Evidence review : liraglutide for the treatment of type 2 diabetes [PDF]

, 2011
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s submission to the National Institute
Cummins, E. (Ewen), HASH(0x5574f4171138), Royle, Pamela, Shyangdan, D. (Deepson), Waugh, Norman   +4 more
core  

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Качество жизни, обусловленное состоянием здоровья лиц пожилого и старческого возраста (обзор литературы)

Качественная клиническая практика, 2018
Результаты исследования качества жизни (КЖ) у пожилых и стариков представляют существенный интерес для современной науки, имеют большое прикладное значение. Эти данные позволяют оценить субъективное восприятие пациентами ситуации, могут быть использованы

doaj  

Obinutuzumab Plus Chemotherapy Compared with Rituximab Plus Chemotherapy in Previously Untreated Italian Patients with Advanced Follicular Lymphoma at Intermediate–High Risk: A Cost-Effectiveness Analysis

ClinicoEconomics and Outcomes Research, 2021
Marco Bellone,1 Lorenzo Pradelli,1 Stefano Molica,2 Adele Emanuela De Francesco,3 Daniela Ghislieri,4 Emanuele Guardalben,5 Antonietta Caputo4 1Department of Health Economics and Outcome Research, AdRes Health Economics and Outcomes Research, Turin ...
Bellone M, Pradelli L, Molica S, De Francesco AE, Ghislieri D, Guardalben E, Caputo A   +6 more
doaj  

Ethical hurdles in the prioritization of oncology care [PDF]

, 2016
With finite resources, healthcare payers must make difficult choices regarding spending and the ethical distribution of funds. Here, we describe some of the ethical issues surrounding inequity in healthcare in nine major European countries, using cancer ...
Capri, Stefano, Castanier, Jean-Claude, Cunningham, David, de Groot, Folkert, Flamion, Bruno, Flume, Mathias, Herholz, Harald, Levin, Lars-Åke, Rupprecht, Christoph J., Shalet, Natalie, Solà-Morales, Oriol, Walker, Andrew, Wong, Olivier   +12 more
core   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

From representing views to representativeness of views: illustrating a new (Q2S) approach in the context of health care priority setting in nine European countries [PDF]

, 2016
Governments across Europe are required to make decisions about how best to allocate scarce health care resources. There are legitimate arguments for eliciting societal vales in relation to health care resource allocation given the roles of the general ...
Adam Kozierkiewicz, Andrea Manca, Angela Robinson, Annika Bergman, Awad Mataria, Cam Donaldson, Cam Donaldson, Christel Protière, Darek Poznanski, Dorte Gyrd-Hansen, Emily Lancsar, Ewa Kocot, Helen Mason, Helen Mason, Jan Abel Olsen, Jean Paul Moatti, Job van Exel, Job van Exel, John Wildman, Jose Luis Pinto Prades, Jytte Seested Nielsen, László Gulácsi, Mark Pennington, Michael Jones-Lee, Mickael Beck, Márta Péntek, Phil Shackley, Philomena Bacon, Rachel Baker, Rachel Baker, Rana Khatib, Roman Topór-Madry, Samer Kharroubi, Stephane Luchini, Sue Bell, Trine Kjaer, Ulf Persson, Werner Brouwer, Werner Brouwer, Yara Jaralla   +39 more
core   +5 more sources

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

Advanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu, Minhui Ouyang, Shufang Tan, Jianlin Guo, Ziqin Zhang, Xuan Liu, Risheng Liu, Hao Huang   +7 more
wiley   +1 more source

Review of methods for assessing the cost-effectiveness of medical interventions

Реальная клиническая практика: данные и доказательства
Assessment of the effectiveness of a drug is a complex process. Currently, the standard method for assessing the effectiveness of a medical intervention is the quality-adjusted life years (QALY).
T. I. Busheva, A. A. Kurylev
doaj   +1 more source