Results 121 to 130 of about 39,340 (291)
Deep Underground Science and Engineering, EarlyView.The graphical abstract illustrates a reconstructed in situ thermo‐hydro‐mechanical (THM) framework in which porosity serves as the central variable linking stress, pore pressure, and temperature to evolving mechanical properties of rocks. Under burial conditions, in situ stress, pore pressure, and temperature jointly govern volumetric strain and ...
Mingyuan Lu +5 more
wiley +1 more source
Trying to estimate a monetary value for qualy [PDF]
In this paper we study the feasibility of estimating a monetary value for a QALY (MVQ). Using two different surveys of the Spanish population (total n=892), we consider whether willingness to pay (WTP) is (approximately) proportional to the health gains ...
Jose Luis Pinto +2 more
core
Ecography, EarlyView.As extreme climatic events are becoming more frequent, we need to understand what mechanisms could buffer populations to ensure their persistence. Fragmented populations may be especially vulnerable, as exemplified by species with metapopulation dynamics whose persistence is determined by a precarious balance between frequent local extinctions and ...
Natalie E. van Dis +5 more
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A steady‐state numerical model is established for a continuous‐flow pH‐TRC for low‐grade waste heat recovery. Based on carbonate and bicarbonate electrolytes, the influences of operating conditions and electrode structure on pH‐driven power generation are clarified.
Jinpeng Hu +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
BMC Oral HealthObjectives Dental caries impacts children’s health- and oral health-related quality of life. Preference-based measures (PBM) can quantify these impacts as utilities, facilitating economic evaluation of interventions.
Helen J. Rogers +3 more
doaj +1 more source
QALYs and Policy Evaluation: A New Perspective [PDF]
This Article presents a new, welfarist defense of the use of QALYs (quality adjusted life years) in policy evaluation. It challenges both the conventional wisdom among health economists that QALY-based analysis is dominated by traditional cost-benefit ...
Adler, Matthew D.
core
ELECTROPHORESIS, EarlyView.Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc +7 more
wiley +1 more source
On the Welfare Economic Foundations of Health Status Measures [PDF]
Measures of health status, such as e.g. the QALY (Quality Adjusted Life Years) measure, have been proposed as a tool in the economic assessment of new medical technologies, and its possible foundations in individual utility theory have been discussed in ...
Hans Keiding, Jens Leth Hougaard
core