Results 41 to 50 of about 93,483 (103)

Convergent Synthesis of Thioether Containing Peptides

open access: yesMolecules, 2020
Thioether containing peptides were obtained following three synthetic routes. In route A, halo acids esterified on 2-chlorotrityl(Cltr) resin were reacted with N-fluorenylmethoxycarbonyl (Fmoc) aminothiols. These were either cleaved from the resin to the
Spyridon Mourtas   +3 more
doaj   +1 more source

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

open access: yesMolecules, 2012
A series of twelve amides was synthesized via aminolysis of substituted pyrazinecarboxylic acid chlorides with substituted benzylamines. Compounds were characterized with analytical data and assayed in vitro for their antimycobacterial, antifungal ...
Katarína Kráľová   +6 more
doaj   +1 more source

Spectroscopic Technique-Based Comparative Investigation on the Interaction of Theaflavins with Native and Glycated Human Serum Albumin

open access: yesMolecules, 2019
Theaflavin is a kind of multi-pharmacological and health beneficial black tea factor. The aim of this study is to investigate the mechanisms by which theaflavin interacts with glycosylated and non-glycosylated serum albumins and compares their binding ...
Jinhui Xu   +3 more
doaj   +1 more source

Comparative Assessment of Phytochemical Profiles of Comfrey (Symphytum officinale L.) Root Extracts Obtained by Different Extraction Techniques

open access: yesMolecules, 2020
In this work a comparative study on phytochemical profiles of comfrey root extracts obtained by different extraction approaches has been carried out.
Nataša Nastić   +4 more
doaj   +1 more source

Eco-friendly Oxidative Iodination of Various Arenes with Sodium Percarbonate as the Oxidantâ€

open access: yesMolecules, 2005
Six easy laboratory procedures are presented for the oxidative iodination ofvarious aromatics, mostly arenes, with either molecular iodine or potassium iodide (usedas the sources of iodinating species, I or I3 ), in the presence of sodium percarbonate ...
Lech Skulski, Agnieszka Zielinska
doaj   +1 more source

Stable Spirocyclic Meisenheimer Complexes

open access: yesMolecules, 2008
Meisenheimer complexes are important intermediates in Nucleophilic Aromatic Substitution Reactions (SNAr). They are formed by the addition of electron rich species to polynitro aromatic compounds or aromatic compounds with strong electron withdrawing ...
Gonzalo Guirado   +2 more
doaj   +1 more source

Molecular Dynamics Simulations of 441 Two-Residue Peptides in Aqueous Solution: Conformational Preferences and Neighboring Residue Effects with the Amber ff99SB-ildn-NMR Force Field.

open access: yesJournal of Chemical Theory and Computation, 2015
Understanding the intrinsic conformational preferences of amino acids and the extent to which they are modulated by neighboring residues is a key issue for developing predictive models of protein folding and stability.
Shuxiang Li   +13 more
semanticscholar   +1 more source

Anti-Inflammatory and Anti-Oxidant Activity of Portulaca oleracea Extract on LPS-Induced Rat Lung Injury

open access: yesMolecules, 2019
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are classified as two lung complications arising from various conditions such as sepsis, trauma, and lung inflammation.
Vafa Baradaran Rahimi   +8 more
doaj   +1 more source

Galgeun-tang Attenuates Cigarette Smoke and Lipopolysaccharide Induced Pulmonary Inflammation via IκBα/NF-κB Signaling

open access: yesMolecules, 2018
Galgeun-tang water extract (GGWE) is used to treat various diseases such as the common cold, eczema and asthma in China and Korea. In this study, we investigated the anti-inflammatory effect of GGWE using a cigarette smoke (CS)- and lipopolysaccharide ...
Na-Rae Shin   +6 more
doaj   +1 more source

Revisiting the Safety of Living Liver Donors by Reassessing 441 Donor Hepatectomies: Is a Larger Hepatectomy Complication‐Prone?

open access: yesAmerican Journal of Transplantation, 2014
Donor safety is of paramount importance in performing living donor liver transplantation (LDLT). We retrospectively reviewed donor medical records to confirm whether larger donor hepatectomy is absolutely complication‐prone.
H. Uchiyama   +10 more
semanticscholar   +1 more source

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