Results 11 to 20 of about 5,809 (168)

Comparison of QF-PCR and FISH for Aneuploidy Detection in Prenatal Diagnosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Among all chromosomes (46) in the human genome, particular significance has been given to chromosomes 13, 18, 21, X and Y. This is primarily because of aneuploidy in these chromosomes that result in viable pregnancies with congenital ...
Sandip C Shah, Nidhi D Shah, Parth S Shah, Hari Shankar P Ray, Ketan K Vaghasia, Anil K Mehta, Bhavini S Shah, Mandava V Rao   +7 more
doaj   +2 more sources

<i>Coxiella burnetii</i> Infection Among Blood Donors From Baden-Wuerttemberg Province and Hesse Province, Germany: A Multicentre Cross-Sectional Serological Study. [PDF]

Public Health Chall
This study analyzes the seroprevalence of Coxiella burnetii in a German non‐risk population using a stratified sampling approach across two federal states (n = 8400 potential samples). Screening of over 5000 blood donors reveals an overall seroprevalence of 2.96%.
Dangel L, Hummel D, Kempf VAJ, Faber M, Hourfar K, Stefan B, Eichner M, Fischer SF.   +7 more
europepmc   +2 more sources

A prenatal case of partial trisomy 21 (q22.2q22.3), resulting from a paternal insertion translocation ins(16;21) and uncovered by QF‐PCR, and characterized by array CGH and FISH [PDF]

Clinical Case Reports, 2018
Key Clinical Message In addition to detecting trisomies of whole chromosomes, QF‐PCR can also detect partial trisomies of the chromosomes 13, 18, and 21, which can suggest an unbalanced translocation.
Shama L. Bhola, Aggie W. M. Nieuwint, Kyra E. Stuurman   +2 more
doaj   +2 more sources

Genetic Evaluation of Spontaneous Miscarriages and Couples through Conventional and Modern Diagnostic Tools [PDF]

Liaquat National Journal of Primary Care, 2023
Background: Genetic causes of miscarriages have been extensively reported and studied in almost half of the first-trimester pregnancy losses, for that reason genetic investigations of the products of conceptions (POCs) are crucial to help identify ...
Misbah Iqbal Hanif, Qaisar Mansoor, Afsheen Arif, Erum Shoeb, Muhammad Ismail, Ayesha Khan, Syed Ajaz Ahmed   +6 more
doaj   +1 more source

Assessment of QF-PCR as the first approach in prenatal diagnosis. [PDF]

J Mol Diagn, 2010
Quantitative fluorescent PCR (QF-PCR) has been used by many laboratories for prenatal diagnosis of the most common aneuploidies. QF-PCR is rapid, cost-effective, and suitable for automation and can detect most abnormalities diagnosed by conventional karyotyping.
Badenas C, Rodríguez-Revenga L, Morales C, Mediano C, Plaja A, Pérez-Iribarne MM, Soler A, Clusellas N, Borrell A, Sánchez MÁ, Miró E, Sánchez A, Milà M, Jiménez W.   +13 more
europepmc   +5 more sources

Chromosome Abnormality Detection Rates of QF-PCR in Early Pregnancy Loss. [PDF]

Curr Health Sci J
Early pregnancy loss (EPL) is the most common form of miscarriage and establishing its exact etiology is vital for the proper prognosis and management of possible future pregnancies. The aim of our study was to assess the incidence and types of chromosome abnormalities in product-of-conception (POC) samples analyzed by Quantitative Fluorescent ...
Popescu-Hobeanu G, Cucu MG, Riza AL, Streata I, Plesea RM, Dorobantu S, Barbu A, Zorila LG, Dinu M, Dijmarescu AL, Tudorache S, Iliescu D, Burada F.   +12 more
europepmc   +3 more sources

A New Stepwise Molecular Work-Up After Chorionic Villi Sampling in Women With an Early Pregnancy Loss

Frontiers in Genetics, 2021
Objective: To explore the use of a new molecular work-up based on the stepwise use of Quantitative Fluorescence PCR (QF-PCR) extended to eight chromosomes and single nucleotide polymorphism array (SNP-array) in chorionic villi obtained by chorionic villi
Montse Pauta, Cèlia Badenas, Laia Rodriguez-Revenga, Anna Soler, Maribel Grande, Joan Sabrià, Carmen Illanes, Virginia Borobio, Antoni Borrell   +8 more
doaj   +1 more source

Detección rápida de aneuploidías para la definición de incompatibilidad con la vida extrauterina independiente

Revista Chilena de Obstetricia y Ginecología, 2022
Objetivo: Analizar la implementación de la prueba rápida de reacción en cadena de la polimerasa cuantitativa y fluorescente (QF-PCR) para la detección de aneuploidías. Método: Se incluyeron todas las pacientes que se realizaron una QFPCR entre septiembre
Fernando Viñals, Eliana Selman, Hugo Guajardo, Katrin Koenig, Gabriel Quiroz, Lorena Hormazábal, Belkys Zambrano, Constanza Saint-Jean, Linder Díaz, Paula Vergara   +9 more
doaj   +1 more source

Segmental Duplications as a Complement Strategy to Short Tandem Repeats in the Prenatal Diagnosis of Down Syndrome [PDF]

Iranian Journal of Medical Sciences, 2019
Background: Quantitative fluorescence-polymerase chain reaction (QF-PCR) is an inexpensive and accurate method for the prenatal diagnosis of aneuploidies that applies short tandem repeats (STRs) as a chromosome-specific marker.
Mohammad Reza Miri, Jamileh Saberzadeh, Abbas Behzad Behbahani, Mohammad Bagher Tabei, Mohsen Alipour, Majid Fardaei   +5 more
doaj   +1 more source

Confirmatory test versus screening test analyses for fetal mosaic variations; a large scale study

Alexandria Journal of Medicine, 2022
Background Mosaic genetic anomaly is a problematic and interpretative issue in prenatal diagnosis. Conventional karyotyping, as a confirmatory test traditionally used for detecting mosaic and nonmosiac prenatal disorders.
Seyed Akbar Moosavi, Behnam Hasannejad-Asl, Masoumeh Kourosh Arami, Mahsa Nasuti, Mehmet Cemal Oguz, Abdol-Hossain Naseri   +5 more
doaj   +1 more source