Results 1 to 10 of about 56,475 (99)

New insights into the treatment of meningoencephalomyelitis of unknown origin since 2009: A review of 671 cases

open access: yesFrontiers in Veterinary Science, 2023
“Meningoencephalomyelitis of unknown origin” (MUO)—a collective term for a group of clinically-indistinguishable (but pathologically distinct) autoimmune diseases of the CNS—has become increasingly commonly recognized throughout the world.
N. Jeffery, N. Granger
semanticscholar   +1 more source

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA [PDF]

open access: yesJournal of Extracellular Vesicles, 2016
Mesenchymal stem cell (MSC), a widely used adult stem cell candidate for regenerative medicine, has been shown to exert some of its therapeutic effects through the secretion of extracellular vesicles (EVs).
Ruenn Chai Lai   +10 more
doaj   +1 more source

Diversity of extracellular vesicles in human ejaculates revealed by cryo-electron microscopy [PDF]

open access: yesJournal of Extracellular Vesicles, 2015
Human ejaculates contain extracellular vesicles (EVs), that to a large extent are considered to originate from the prostate gland, and are often denominated “prostasomes.” These EVs are important for human fertility, for example by promoting sperm ...
Johanna L. Höög, Jan Lötvall
doaj   +1 more source

Optimized culture methods for isolating small extracellular vesicles derived from human induced pluripotent stem cells

open access: yesJournal of Extracellular Vesicles, 2021
Extracellular vesicles that are derived from stem cells play an important role in the treatment of disease. To obtain high‐quality small extracellular vesicles (sEVs), we optimized the culture conditions of human induced pluripotent stem cells (hiPSCs ...
Ying Luo   +6 more
doaj   +1 more source

Downregulation of lncRNA SATB2‑AS1 facilitates glioma cell proliferation by sponging miR‑671‑5p

open access: yesExperimental and Therapeutic Medicine, 2023
The antisense transcript of SATB2 protein (SATB2-AS1) is a novel long non-coding RNA (lncRNA) which is involved in the development of colorectal cancer, breast cancer and hepatocellular carcinoma.
Jia Gu   +4 more
semanticscholar   +1 more source

Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR‐671‐5p/LGALS3BP/NF‐κB axis

open access: yesCancer Science, 2023
Circular RNAs (circRNAs) play crucial roles in various biological processes, including prostate cancer (PCa). However, the precise roles and mechanism of circRNAs are complicated.
Kaixuan Guo   +7 more
semanticscholar   +1 more source

Identification of miR-671-5p and Its Related Pathways as General Mechanisms of Both Form-Deprivation and Lens-Induced Myopia in Mice

open access: yesCurrent Issues in Molecular Biology, 2023
Animal models have been indispensable in shaping the understanding of myopia mechanisms, with form-deprivation myopia (FDM) and lens-induced myopia (LIM) being the most utilized.
Zedu Cui   +10 more
semanticscholar   +1 more source

miR-152-3p impedes the malignant phenotypes of hepatocellular carcinoma by repressing roundabout guidance receptor 1

open access: yesCellular & Molecular Biology Letters, 2022
Background miR-152-3p functions as a tumour suppressor in the progression of hepatic tumorigenesis. Herein, we further discussed the prognostic significance and immune infiltration of miR-152-3p and its potential gene target in hepatocellular carcinoma ...
Tao Yin, Haonan Zhao
doaj   +1 more source

Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis

open access: yesCellular & Molecular Biology Letters, 2022
Despite great advances, therapeutic approaches of osteosarcoma, the most prevalent class of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to demonstrate insufficient adequacy.
Mina Homayoonfal   +2 more
doaj   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

open access: yesJournal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu   +12 more
semanticscholar   +1 more source

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