Results 31 to 40 of about 56,475 (99)

Exosomes derived from clinical-grade oral mucosal epithelial cell sheets promote wound healing

open access: yesJournal of Extracellular Vesicles, 2019
The oral mucosa exhibits unique regenerative properties, sometimes referred to as foetal-like wound healing. Researchers from our institute have used sheets of oral mucosa epithelial cells (OMECs) for regenerative medicine applications including cornea ...
Sebastian Sjöqvist   +7 more
doaj   +1 more source

Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming

open access: yesCell Discovery, 2021
Paternal life experiences impact offspring health via germline, and epigenetic inheritance provides a potential mechanism. However, global reprogramming during offspring embryogenesis and gametogenesis represents the largest hurdle to conceptualize it ...
Xiaoguo Zheng   +8 more
doaj   +1 more source

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

open access: yesCell Death and Disease, 2021
Breast cancer is the most common cancer in the world. Relapse and metastasis are important factors endangering the life of breast cancer patients, but the mechanism is still unclear.
Yafei Guo   +10 more
doaj   +1 more source

Src acts as the target of matrine to inhibit the proliferation of cancer cells by regulating phosphorylation signaling pathways

open access: yesCell Death and Disease, 2021
Studies have shown that matrine has antitumor activity against many types of cancers. However, the direct target in cancer cells of its anticancer effect has not been identified.
Xi Zhang   +7 more
doaj   +1 more source

Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution

open access: yesCell Death and Disease, 2021
Ischemia–reperfusion injury (IRI) remains the major reason for impaired donor graft function and increased mortality post-liver transplantation. The mechanism of IRI involves multiple pathophysiological processes and numerous types of cells.
Linhe Wang   +14 more
doaj   +1 more source

How Do Climate and Catchment Attributes Influence Flood Generating Processes? A Large‐Sample Study for 671 Catchments Across the Contiguous USA

open access: yesWater Resources Research, 2021
Hydrometeorological flood generating processes (excess rain, short rain, long rain, snowmelt, and rain‐on‐snow) underpin our understanding of flood behavior.
Lina Stein   +4 more
semanticscholar   +1 more source

Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner

open access: yesCell Death and Disease, 2021
Hyaluronan (HA) cross-linking is a conformational state of HA, a covalent complex between HA and heavy chains (HCs) from inter-α-trypsin inhibitor (I-α-I) mediated by tumor necrosis factor-induced protein 6 (TSG6).
Guoliang Zhang   +5 more
doaj   +1 more source

A review on the role of miR-671 in human disorders

open access: yesFrontiers in Molecular Biosciences, 2022
miR-671 is encoded by a gene on 7q36.1 and contributes to the pathogenesis of a variety of disorders, including diverse types of cancers, atherosclerosis, ischemic stroke, liver fibrosis, osteoarthritis, Parkinson’s disease, rheumatoid arthritis, acute ...
S. Ghafouri-Fard   +6 more
semanticscholar   +1 more source

Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1

open access: yesCell Death and Disease, 2021
Long noncoding RNAs (lncRNAs) emerge as essential roles in the regulation of alternative splicing (AS) in various malignancies. Serine- and arginine-rich splicing factor 1 (SRSF1)-mediated AS events are the most important molecular hallmarks in cancer ...
Yuqing Duan   +8 more
doaj   +1 more source

HJURP promotes proliferation in prostate cancer cells through increasing CDKN1A degradation via the GSK3β/JNK signaling pathway

open access: yesCell Death and Disease, 2021
Genes with cross-cancer aberrations are most likely to be functional genes or potential therapeutic targets. Here, we found a total of 137 genes were ectopically expressed in eight cancer types, of which Holliday junction recognition protein (HJURP) was ...
Wenjie Lai   +9 more
doaj   +1 more source

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