Results 51 to 60 of about 4,586 (212)
Differential fitness costs of different qnr determinants.
Plasmid loss was measured in the acrAB defective E. coli KZM120 strain (black bars), in the wild-type strain E. coli MC4100 (gray bars) and in the hns defective E. coli JMG100 strain (white bars). pGEM-T, empty vector; pBS3.25, plasmid with Smqnr; pBS18,
María B. Sánchez (166312) +1 more
core +1 more source
In-vitro mutagenesis of qnrA and qnrS genes and quinolone resistance in Escherichia coli [PDF]
Plasmid-mediated quinolone resistance is being reported increasingly worldwide among isolates of enterobacteria. This resistance is mostly associated with Qnr-like determinants that confer resistance to quinolones, e.g., nalidixic acid, and reduced susceptibility to fluoroquinolones. This study investigated whether amino-acid substitutions in QnrA1 and
Cattoir, V., Poirel, L., Nordmann, P.
openaire +2 more sources
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento +13 more
wiley +1 more source
Cefotaxime-Resistant Salmonella enterica in Travelers Returning from Thailand to Finland
During 1993–2011, cefotaxime resistance among Salmonella enterica isolates from patients in Finland increased substantially. Most of these infections originated in Thailand; many were qnr positive and belonged to S.
Marianne Gunell +8 more
doaj +1 more source
Mechanisms of quinolone resistance and implications for human and animal health [PDF]
Quinolone antibiotics have been widely used in human and veterinary medicine. This has caused the development of resistance and difficulties in the treatment of complicated bacterial infections in humans.
Velhner Maja +5 more
doaj +1 more source
ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a potentially long‐term consequence of oxaliplatin‐based chemotherapy for colorectal cancer (CRC). Oxaliplatin dosing is based on body surface area (BSA), but lean body mass (LBM) may influence susceptibility to long‐term CIPN.
Nadira R. Querido +10 more
wiley +1 more source
Inhibition of QNR cell differentiation correlates with TGF-β3 down-regulation by v-Src.
(A) QPCR analysis of TGF-β3 mRNA levels in 7-day-old (E7) embryonic QNR seeded for 1 (E7+1), 8 (E7+8) or 18 (E7+18) days. Results were normalized based on HPRT and TBP transcript levels and presented in relative arbitrary units, using values obtained for
Samira Amarir (360555) +2 more
core +1 more source
ABSTRACT Livestock manure is a valuable agricultural resource but may introduce antibiotic residues and antibiotic resistance genes (ARGs) into the environment. This review critically evaluates the fate of antibiotics and ARGs during manure composting and identifies the principal factors controlling their attenuation.
Magdalena Urbaniak
wiley +1 more source
Establishment of multiplex PCR for detection of genes related to Quinolone resistance
Background/aims: It has been shown that quinolone resistance arises due to mutations in the quinolone resistance-determining regions of the drug targets.
Ngo Tat Trung +4 more
doaj +1 more source
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman +5 more
wiley +1 more source

