Results 291 to 300 of about 1,004,764 (341)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Antiapoptotic BCL2 family proteins BCL-XL and MCL1 as factors predicting resistance against venetoclax plus azacitidine for patients with newly diagnosed acute myelogenous leukemia. [PDF]

PLoS One
Kamihara Y, Kikuchi S, Ishikawa N, Shinomiya N, Kunimoto K, Horaguchi R, Fujihira T, Nabe Y, Minemura T, Ono K, Wada A, Dang NH, Sato T.   +12 more
europepmc   +1 more source

Primers used for RT-qPCR analysis.

Fang Wu (267711), Jing Zhang (23775), Hongshan Yang (11605182), Huirong Duan (11605184)   +3 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A PNPLA3-NACC1-RIPK3 pathway mediates macrophage necroptosis and inflammation in MASLD. [PDF]

Hepatol Commun
Wang X, Bian L, Feng Z, O'Shaughnessy K, Kwong AC, Ha EH, Wang L, Chen W, Wu X.   +8 more
europepmc   +1 more source

List of primers for RT-qPCR.

Jing Chen (4762), Lin han Zhong (22784203), Jin xia Chen (22784206), Hui xin Song (22784209), Lin ke Zou (22784212), Xiao qing Bi (22784215), Bing qian Zhao (22784218), Mei zhen Li (22784221), Kun Li (277035), Kang Wang (415359), Jia jun Yang (22784224), Jin Cui (638547), Li Wang (15202), Bin Zhou (84959)   +13 more
openalex   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Establishment of a TaqMan multiplex quantitative PCR method for detecting three different serovars of Glaesserella parasuis serovars 5/12, 7 and 11. [PDF]

BMC Vet Res
Zhendong W, Hao Y, Lumen C, Yufeng L.
europepmc   +1 more source

Raw data and statistical results for RT-qPCR analysis related to Fig 11.

Nobuyoshi Kumagai (7829759), Michio Kuroda (22641220), Tosei Hanai (22641223), Masaki Fujita (25710), Takaaki Hino (22641226), Shunta Yorimoto (22641229), Sayaka Manta (22641232), Shuzo Nakagawa (22641235), Moe Yokoyama (22641238), Leon Tajima (22641241), Riku Ito (22641244), Hikaru Yamada (22641247), Kota Miura (53551), Makoto Kashima (7369595), Katsushi Yamaguchi (535058), Shuji Shigenobu (464699), Ryohei Furukawa (610857), Kiyono Sekii (5384378), Kazuya Kobayashi (845603)   +18 more
openalex   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source