Results 61 to 70 of about 647,340 (267)

Molecular identification, typing, and virulence gene profiling of salmonella isolates recovered from cattle and buffaloes in egypt [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi
Salmonella is a major cause of diarrhea in cattle and buffaloes. This study aimed to isolate and biochemically identify Salmonella species from faeces of cattle and buffaloes, confirm and type isolated Salmonella species molecularly, determine Salmonella
Amany Dieb BAHR   +7 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Patient qPCR Data

open access: yes, 2020
Patient qPCR ...
Doolan, Lara   +4 more
openaire   +1 more source

Molecular Detection and characterization of viruses infecting greenhouse-grown tomatoes in Albania

open access: yesPhytopathologia Mediterranea
During the 2023–2024 growing season, a total of 45 tomato greenhouses were visited across five major production regions of Albania (Berat, Lushnje, Fier, Tirana, and Shkodra). A total of 196 greenhouse-grown tomato leaf samples, representing 31 varieties,
Magdalena CARA   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

qPCR Workshop

open access: yes, 2014
Workshop on qPCR sample preparation, primer design, primer optimalisation, qPCR setup and data analysis. Machine set-up specific for ABI 7300. Data analysis with LinRegPCR.
openaire   +1 more source

Expression analysis of the porcine Homeobox A11 gene and its association with litter size in Large White pigs

open access: yesCzech Journal of Animal Science, 2016
The homeobox A11 (HOXA11) gene, a well-known transcriptional regulator, plays a critical role in normal development of the uterus. In this study, the porcine HOXA11 gene, including its promoter region, was cloned and sequenced (GenBank Accession No ...
R. Lin, H. Jia, S. Chen, S. Zhao
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Brief guide to RT-qPCR

open access: yesMolecules and Cells
RNA quantification is crucial for understanding gene expression and regulation. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is a widely used technique for RNA quantification because of its practical and quantitative nature, sensitivity, and specificity.
Bong, Dajeong   +2 more
openaire   +2 more sources

Quantitative polymerase chain reaction detection of hemotropic and vector-borne pathogens in dogs and cats using blood and pooled blood–urine matrixes: A large-scale retrospective study in Colombia [PDF]

open access: yesVeterinary World
Background and Aim: Hemotropic and vector-borne pathogens are important causes of disease in dogs and cats, particularly in tropical regions. Whole blood is conventionally used for molecular diagnosis; however, fluctuating pathogen loads may reduce ...
Juan Fernando Manrique-Hincapie   +4 more
doaj   +1 more source

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