Results 51 to 60 of about 932,733 (312)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Discriminating between viable and membrane-damaged cells of the plant pathogen Xylella fastidiosa. [PDF]

open access: yes, 2019
Xylella fastidiosa is a plant pathogenic bacterium with devastating consequences to several crops of economic importance across the world. While this pathogen has been studied for over a century in the United States, several aspects of its biology remain
Almeida, Rodrigo   +5 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Phytoplankton Community and Algal Toxicity at a Recurring Bloom in Sullivan Bay, Kabetogama Lake, Minnesota, USA [PDF]

open access: yes, 2019
Kabetogama Lake in Voyageurs National Park, Minnesota, USA suffers from recurring late summer algal blooms that often contain toxin-producing cyanobacteria.
Christensen, Victoria G.   +4 more
core   +2 more sources

Quantification of type II procollagen splice forms using alternative transcript-qPCR (AT-qPCR) [PDF]

open access: yesMatrix Biology, 2012
During skeletal development, the onset of chondrogenic differentiation is marked by expression of the α1(II) procollagen (Col2a1) gene. Exon 2 of Col2a1 codes for a cysteine-rich von Willebrand factor C-like domain. Chondroprogenitors express the exon 2-containing IIA and IID splice forms by utilizing adjacent 5' splice sites separated by 3 base pairs.
Audrey, McAlinden   +4 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A study of the relationship between the Galectin-9 gene (LGALS9) in three types of cancer patients in Basrah, Iraq [PDF]

open access: yesRomanian Journal of Medical Practice
Background. One essential member of the galectin family, galactose lectin-9 (Gal-9) serves several functions as a multi-subtype lectin. According to the latest research, tumor interaction with Gal-9 is a separate component that affects how quickly tumors
Anwar N. AYOOB   +2 more
doaj   +1 more source

Integrated microsystems for molecular pathology [PDF]

open access: yes, 2011
We have integrated electronic, optical, magnetic, thermal and fluidic devices into systems to construct useful analysis tools. Over the past several years, we have developed soft lithography approaches to define microfluidic systems in which pico-Liter ...
Kartalov, Emil   +3 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Discrimination of haploids and doubled haploids/diploids in indica rice: correlation of morphological indicators with molecular markers

open access: yesBiologia Plantarum, 2023
To obtain immediate homozygosity by androgenesis, the doubled haploid method is often used. As a result, a mapping population was created utilizing rice (Oryza sativa L.) cvs.
S.K. Singh   +9 more
doaj   +1 more source

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