Results 21 to 30 of about 7,147 (203)

Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1-KO mouse models

open access: yesFrontiers in Neuroscience, 2023
IntroductionAutism spectrum disorder (ASD) is a persistent neurodevelopmental condition characterized by two core behavioral symptoms: impaired social communication and interaction, as well as stereotypic, repetitive behavior. No distinct cause of ASD is
Shirin Sharghi   +9 more
doaj   +1 more source

Metopimazine is primarily metabolized by a liver amidase in humans

open access: yesPharmacology Research & Perspectives, 2022
Metopimazine (MPZ) is a peripherally restricted, dopamine D2 receptor antagonist used for four decades to treat acute nausea and vomiting. MPZ is currently under clinical investigation for the treatment of gastroparesis (GP).
Robert W. Busby   +8 more
doaj   +1 more source

Vibration Signal Parameter Estimation in Variable Speed: Algorithms and performance bounds

open access: yesENP Engineering Science Journal, 2021
Vibration signal parameter estimation for rotating machinery diagnostics operating under variable speed conditions is considered. At first, we provide a brief survey of existing methods for Quadratic Phase Signal (QPS) parameter estimation.
Ali Abbadi   +3 more
doaj   +1 more source

Romans Massive QP Manifolds [PDF]

open access: yesUniverse, 2022
We introduce QP manifolds that capture the generalised geometry of type IIA string backgrounds with Ramond–Ramond fluxes and Romans mass. Each of these is associated with a BPS brane in type IIA: a D2, D4, or NS5-brane. We explain how these probe branes are related to their associated QP-manifolds via the AKSZ topological field theory construction and ...
Alex S. Arvanitakis   +2 more
openaire   +4 more sources

Region-dependent bidirectional plasticity in M1 following quadripulse transcranial magnetic stimulation in the inferior parietal cortex

open access: yesBrain Stimulation, 2020
Background: The ability to manipulate the excitability of the network between the inferior parietal lobule (IPL) and primary motor cortex (M1) may have clinical value.
Fuminari Kaneko   +3 more
doaj   +1 more source

Decreased plasma Aβ in hyperlipidemic APPSL transgenic mice is associated with BBB dysfunction

open access: yesFrontiers in Neuroscience, 2016
Besides the continued focus on Aβ and Tau in Alzheimer’s disease (AD), it is increasingly evident that other pathologic characteristics, such as vascular alterations or inflammation, are associated with AD.
Tina eLöffler   +3 more
doaj   +1 more source

CURRENT ALGEBRAS AND QP-MANIFOLDS [PDF]

open access: yesInternational Journal of Geometric Methods in Modern Physics, 2013
Generalized current algebras introduced by Alekseev and Strobl in two dimensions are reconstructed by a graded manifold and a graded Poisson brackets. We generalize their current algebras to higher dimensions. QP-manifolds provide the unified structures of current algebras in any dimension.
Ikeda, Noriaki, Koizumi, Kozo
openaire   +2 more sources

Phosphorylation of different tau sites during progression of Alzheimer’s disease

open access: yesActa Neuropathologica Communications, 2018
Alzheimer’s disease is characterized by accumulation of amyloid plaques and tau aggregates in several cortical brain regions. Tau phosphorylation causes formation of neurofibrillary tangles and neuropil threads.
Joerg Neddens   +9 more
doaj   +1 more source

Quadripulse transcranial magnetic stimulation inducing long-term depression in healthy subjects may increase seizure risk in some patients with intractable epilepsy

open access: yesClinical Neurophysiology Practice, 2023
Objective: This study aimed to assess the efficacy and safety of quadripulse transcranial magnetic stimulation-50 (QPS-50) in patients with intractable epilepsy. Methods: Four patients were included in the study.
Setsu Nakatani-Enomoto   +13 more
doaj   +1 more source

Hepatic and neuronal phenotype of NPC1−/− mice

open access: yesHeliyon, 2019
Niemann-Pick type C disease (NPC) is a fatal autosomal recessive disorder characterized by a defect in the intracellular transport of lipoproteins leading to the accumulation of lipids in diverse tissues. A visceral and neuronal phenotype mimicking human
Estibaliz Santiago-Mujica   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy