Results 41 to 50 of about 8,144 (201)

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 18: Suitability of taxonomic units notified to EFSA until March 2023

EFSA Journal, 2023
The qualified presumption of safety (QPS) approach was developed to provide a regularly updated generic pre‐evaluation of the safety of microorganisms, intended for use in the food or feed chains, to support the work of EFSA's Scientific Panels.
EFSA Panel on Biological Hazards (BIOHAZ), Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Alessandra De Cesare, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Romolo Nonno, Luísa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Fulvio Barizzone, Sandra Correia, Lieve Herman   +26 more
doaj   +1 more source

Evaluation of Skin Penetration of Diclofenac from a Novel Topical Non Aqueous Solution: A Comparative Bioavailability Study [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Different topical formulations of diclofenac have varying skin penetration profile. Recent advances in science and technology has led to the development of many new formulations of drugs for topical drug delivery. One such technological
Manish Nivsarkar, Sanjaykumar H. Maroo, Ketan R. Patel, Dixit D. Patel   +3 more
doaj   +1 more source

Thermodynamics of Concomitant Charge‐Transfer, Antiferromagnetic, and Isostructural Phase Transitions in Barocaloric ACu3Fe4O12 Quadruple Perovskites

Advanced Science, EarlyView.
A copper‐iron charge transfer instability drives concomitant electronic, magnetic, and isostructural phase transitions in ACu3Fe4O12${\rm ACu}_3{\rm Fe}_4{\rm O}_{12}$, with an inverse barocaloric effect. A minimal Landau theory ties these thermodynamic signatures together, revealing a pressure‐independent transition entropy with comparable charge and ...
Jefferson Delgado‐Quesada, Gian Giacomo Guzmán‐Verri   +1 more
wiley   +1 more source

A facile preparation of a novel non-leaching antimicrobial waterborne polyurethane leather coating functionalized by quaternary phosphonium salt

Journal of Leather Science and Engineering, 2020
The aim of this research is to develop a novel non-leaching antimicrobial waterborne polyurethane (WPU) leather coating material with covalently attached quaternary phosphonium salt (QPS).
Chunhua Wang, Jianhui Wu, Li Li, Changdao Mu, Wei Lin   +4 more
doaj   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Implementation of the IBD-QPS

, 2022
This study will use a previously pilot tested IBD-QPS in a population of people with IBD previously recruited. The tool will be given one week prior to the specilaist appointment to the patient at two participanting sites (The Wollongong Hospital and St.
Chiara Miglioretto
core   +1 more source

Updated list of QPS-recommended microorganisms for safety risk assessments carried out by EFSA

, 2023
The European Food Safety Authority (EFSA) asked the Panel on Biological Hazards (BIOHAZ) to deliver a scientific Opinion on the maintenance of the list of qualified presumption of safety (QPS) biological agents. The QPS approach was developed by the EFSA
Hilbert, Friederike, Barizzone, Fulvio, Correia, Sandra, De Cesare, Alessandra, Skandamis, Panagiotis, Koutsoumanis, Konstantinos, Nauta, Maarten, Maradona, Miguel Prieto, Bover-Cid, Sara, Vlak, Just, EFSA BIOHAZ Panel, Suffredini, Elisabetta, Cocconcelli, Pier Sandro, Allende, Ana, Peixe, Luisa, Lindqvist, Roland, Alvarez-Ordonez, Avelino, Chemaly, Marianne, Bolton, Declan, Sijtsma, Lolke, Sundh, Ingvar, Ru, Giuseppe, Querol, Amparo, Simmons, Marion, Herman, Lieve, Suarez, Juan Evaristo, Fernández Escámez, Pablo Salvador   +26 more
core   +2 more sources

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Physicochemical Properties, Antioxidant and Antidiabetic Activities of Polysaccharides from Quinoa (Chenopodium quinoa Willd.) Seeds

Molecules, 2020
Quinoa is known for its rich nutrients and bioactive compounds. In order to elucidate the preliminary structural characteristics and biological activity of polysaccharides from quinoa (QPs), five crude polysaccharides (QPE50, QPE60, QPE70, QPE80 and ...
Minghui Tan, Senlin Chang, Jianing Liu, Hang Li, Pengwei Xu, Peidong Wang, Xiaodong Wang, Mingxia Zhao, Bing Zhao, Liwei Wang, Qingsheng Zhao   +10 more
doaj   +1 more source

Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women

British Journal of Clinical Pharmacology, EarlyView.
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea, Andrew Litovsky, Prachi Wickremasingha, Nairita Ghosal, Brad Roadcap, Robert Valesky, Robin Lee, Leea D. Reed, Ming Wang, Wei Fang, Rebecca Wrishko   +10 more
wiley   +1 more source