Phosphorylation of different tau sites during progression of Alzheimer’s disease
Acta Neuropathologica Communications, 2018 Alzheimer’s disease is characterized by accumulation of amyloid plaques and tau aggregates in several cortical brain regions. Tau phosphorylation causes formation of neurofibrillary tangles and neuropil threads.
Joerg Neddens +9 more
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Influence of phasic muscle contraction upon the quadripulse stimulation (QPS) aftereffects
Clinical Neurophysiology, 2015 Suguru Kadowaki +5 more
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Hepatic and neuronal phenotype of NPC1−/− mice
Heliyon, 2019 Niemann-Pick type C disease (NPC) is a fatal autosomal recessive disorder characterized by a defect in the intracellular transport of lipoproteins leading to the accumulation of lipids in diverse tissues. A visceral and neuronal phenotype mimicking human
Estibaliz Santiago-Mujica +5 more
doaj +1 more source
Improved bioavailability of cromolyn sodium using inhaled PA101 delivered via eFlow® nebulizer
European Clinical Respiratory Journal, 2020 In 1960s, cromolyn sodium (CS) has been introduced as the first non-steroidal anti-inflammatory drug for the treatment of allergic and mast-cell driven diseases. Its applicability has been limited due to a poor bioavailability.
Khalid Abd-Elaziz +2 more
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Clinical Neurophysiology Practice, 2023 Objective: This study aimed to assess the efficacy and safety of quadripulse transcranial magnetic stimulation-50 (QPS-50) in patients with intractable epilepsy. Methods: Four patients were included in the study.
Setsu Nakatani-Enomoto +13 more
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Quercetin 3, 3′, 4′, 5, 7-O- pentasulfate (QPS): A novel activator of protein disulfide isomerase
Medicine in Drug Discovery, 2020 Aims: Design and synthesis of a novel 3, 3′, 4′, 5, 7-O- pentasulfated Quercetin (QPS) as an activator of protein disulfide isomerase (PDI). Main Methods: Based on an in silico analysis we show that QPS binds to a and b domain of PDI (−7.4 kcal/mol ...
Abdul Burhan Khan +7 more
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Blueprints in biochemistry: Systematic assessment in undergraduate medical education [PDF]
Research and Development in Medical Education, 2022 Background: The traditional pattern of theory assessment may not address the principles of assessment due to faulty paper-setting practices. This interventional study aimed to sensitize the faculty in designing a test blueprint template to set question ...
Yogesh R. Pawade +2 more
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Quantum phase slips in the presence of finite-range disorder [PDF]
, 2005 To study the effect of disorder on quantum phase slips (QPS) in superconducting wires, we consider the plasmon-only model where disorder can be incorporated into a first-principles instanton calculation. We consider weak but general finite-range disorder
I. O. Kulik +6 more
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Gal(Qp/Qp) as a geometric fundamental group [PDF]
International Mathematics Research Notices, 2016 Let p be a prime number. In this article we present a theorem, suggested by Peter Scholze, which states that Gal(Qp/Qp) is the etale fundamental group of certain object Z which is defined over an algebraically closed field. As a consequence, p-adic representations of Gal(Qp/Qp) correspond to Qp-local systems on Z.
openaire +1 more source
Scientific Opinion on the maintenance of the list of QPS biological agents intentionally added to food and feed (2012 update) [PDF]
EFSA Journal, 2012 EFSA is requested to assess the safety of a broad range of biological agents in the context of notifications for market authorisation as sources of food and feed additives, enzymes and plant protection products.
EFSA Panel on Biological Hazards (BIOHAZ)
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