Results 71 to 80 of about 23,998 (251)

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 5: suitability of taxonomic units notified to EFSA until September 2016

EFSA Journal, 2017
EFSA was requested to assess the safety of a broad range of biological agents in the context of notifications for market authorisation as sources of food and feed additives, enzymes and plant protection products. The qualified presumption of safety (QPS)
EFSA Panel on Biological Hazards (BIOHAZ), Antonia Ricci, Ana Allende, Declan Bolton, Marianne Chemaly, Robert Davies, Rosina Girones, Kostas Koutsoumanis, Lieve Herman, Roland Lindqvist, Birgit Nørrung, Lucy Robertson, Giuseppe Ru, Moez Sanaa, Marion Simmons, Panagiotis Skandamis, Emma Snary, Niko Speybroeck, Benno Ter Kuile, John Threlfall, Helene Wahlström, Pier Sandro Cocconcelli, Günter Klein (deceased), Luisa Peixe, Miguel Prieto Maradona, Amparo Querol, Juan Evaristo Suarez, Ingvar Sundh, Just Vlak, Sandra Correia, Pablo Salvador Fernández Escámez   +30 more
doaj   +1 more source

Improved analysis of algorithms based on supporting halfspaces and quadratic programming for the convex intersection and feasibility problems [PDF]

, 2014
This paper improves the algorithms based on supporting halfspaces and quadratic programming for convex set intersection problems in our earlier paper in several directions.
Pang, C. H. Jeffrey
core  

Scope ambiguities, monads and strengths

, 2016
In this paper, we will discuss three semantically distinct scope assignment strategies: traditional movement strategy, polyadic approach, and continuation-based approach.
Grudzinska, Justyna, Zawadowski, Marek
core   +2 more sources

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

Cancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa, Takeshi Wakasa, Yuki Kataoka, Koji Ando, Eiji Oki, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao   +7 more
wiley   +1 more source

Efficacy and safety of quick penetrating solution heparin, quick penetrating solution diclofenac, and heparin gel in the prevention of infusion-associated superficial thrombophlebitis: A randomized controlled trial

Perspectives in Clinical Research
Background The present study aimed to compare the efficacy, safety, and cost-effectiveness of quick penetrating solution (QPS) heparin, QPS diclofenac, and heparin gel in the prevention of superficial thrombophlebitis (ST).
Vijeta Bajpai, Tejas K. Patel, Priyanka Dwivedi, Ankita Kabi, Yashpal Singh, Richa Agarwal, Ravi Gupta, Surekha Kishore   +7 more
doaj   +1 more source

Plasticity induction in the pre-supplementary motor area (pre-SMA) and SMA-proper differentially affects visuomotor sequence learning

Brain Stimulation, 2020
Background: Both pre-supplementary motor area (pre-SMA) and SMA-proper (SMA) must play important roles in visuomotor sequence learning. However, functional differences between the pre-SMA and SMA have not been well studied in humans.
Takahiro Shimizu, Ritsuko Hanajima, Yuichiro Shirota, Ryosuke Tsutsumi, Nobuyuki Tanaka, Yasuo Terao, Masashi Hamada, Yoshikazu Ugawa   +7 more
doaj   +1 more source

A positive feedback loop between two C-type lectins originated from gene duplication and relish promotes the expression of antimicrobial peptides in Procambarus clarkii

Frontiers in Immunology, 2022
Gene duplication (GD) leads to the expansion of gene families that contributes organisms adapting to stress or environment and dealing with the infection of various pathogens. C-type lectins (CTLs) in crustaceans undergo gene expansion and participate in
Xiaoling Dai, Mengling Sun, Ximei Nie, Yuqi Zhao, Hao Xu, Zhengxiao Han, Tianheng Gao, Xin Huang, Qian Ren   +8 more
doaj   +1 more source

A phase 1 study of the breast milk and plasma pharmacokinetics of zavegepant 10 mg intranasal dose in healthy lactating women

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study evaluated the pharmacokinetics of zavegepant in human breast milk and plasma following a single, 10 mg dose of zavegepant nasal spray. Background Zavegepant nasal spray is a member of the gepant class of medications; small molecule inhibitors of the calcitonin gene‐related peptide receptor.
Abhijeet Jakate, Yan Weng, Ani Shkrodova, Ogert Fisniku, Ding Ding, Kayce Morton, Benjamin Maligalig, Pamela Garnick, Jing Liu, Mohamed H. Shahin   +9 more
wiley   +1 more source

Detecting Non-Abelian Anyons by Charging Spectroscopy

, 2012
Observation of non-Abelian statistics for the e/4 quasiparticles in the \nu=5/2 fractional quantum Hall state remains an outstanding experimental problem.
Ben-Shach, Gilad, Halperin, Bertrand I., Laumann, Chris R., Neder, Izhar, Yacoby, Amir   +4 more
core   +1 more source