Results 61 to 70 of about 76,897 (289)

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Repurposing Anti-diabetic Drugs to Cripple Quorum Sensing in Pseudomonas aeruginosa

Microorganisms, 2020
Pseudomonas aeruginosa is a significant human pathogen, it possesses almost all of the known antimicrobial resistance mechanisms. Quorum sensing (QS) is an intercellular communication system that orchestrates bacterial virulence and its targeting is an ...
Wael A. H. Hegazy, Maan T. Khayat, Tarek S. Ibrahim, Majed S. Nassar, Muhammed A. Bakhrebah, Wesam H. Abdulaal, Nabil A. Alhakamy, Mahmoud M. Bendary   +7 more
doaj   +1 more source

Square root of fuzzy QS-ideals on QS-algebras

Iraqi Journal of Science
In real-life problems, we use square roots in natural distributions such as (the probability density function), distances and lengths in the Pythagorean theorem, and quadratic formulas in (the height of falling objects), radius of circles, harmonic movements (pendulum and springs), and standard deviation in statistics. We have observed that using fuzzy
Samy M. Mostafa, Mostafa A. Hassan, Fatema F. Kareem   +2 more
openaire   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Synthesis of QS-21-Based Immunoadjuvants [PDF]

The Journal of Organic Chemistry, 2013
Three structurally defined QS-21-based immune adjuvant candidates (2a-2c) have been synthesized. Application of the two-stage activation glycosylation approach utilizing allyl glycoside building blocks improved the synthetic accessibility of the new adjuvants.
Pengfei, Wang, Qipu, Dai, Punith, Thogaripally, Ping, Zhang, Suzanne M, Michalek   +4 more
openaire   +2 more sources

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

UPC es reconocida internacionalmente con la más alta calificación en cuatro categorías del QS Stars 2015

, 2015
Consciente de la importancia de brindar una enseñanza exigente y con estándares de calidad de nivel internacional, la Universidad Peruana de Ciencias Aplicadas (UPC) participó en la evaluación QS Stars de la prestigiosa agencia calificadora británica ...

core   +3 more sources

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

(1/2,1/2)-Fuzzy QS–ideals and its correlation coefficients [PDF]

Journal of Hyperstructures
As an extension of intuitionistic fuzzy sets, we introduce the notion of -fuzzy set ( denoted by SSR) of QS -ideals on a OS -algebra and investigate its properties.
Mostafa Hassan, Samy Mostafa
doaj   +1 more source

How Covid-19 is Impacting Prospective International Students at Different Study Levels

, 2020
The coronavirus (COVID-19) crisis has rapidly reshaped how universities operate, teach, communicate, and recruit in the last few months. This report explores how prospective international students are addressing the challenges raised by the coronavirus ...
QS
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