Results 81 to 90 of about 76,897 (289)

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

強震動の二重スペクトル比から推定した九州南部におけるQs値 [PDF]

open access: yes, 2000
九州南部におけるK-NET観測点での強震記録を解析し,S波の減衰に関するQs値について調べた.2つの地震の際の2つの観測点での記録の二重スペクトル比をとることによって,震源の影響と観測点での地盤の影響を取り除いて,伝播経路の影響だけを孤立させることができる.本研究で得られたQs値は過去の研究で得られている値の1/2~1/3程度である.Qs値が小さく求まった現員としては,過去の研究に比べて伝播経路がかなり浅いことと,霧島火山帯の下を通過する経路であることが考えられる.Qs値は深さによって,また ...
泉谷, 恭男
core  

Impedance‐Matched High‐Overtone Thickness‐Shear Bulk Acoustic Resonators With Scalable Mode Volume

open access: yesAdvanced Science, EarlyView.
A bottom‐electrode‐free high‐overtone bulk acoustic resonator is achieved by lateral excitation of antisymmetric thickness‐shear modes on a lithium‐niobate‐on‐silicon platform. Planar electrode geometry eliminates conventional loading along the resonance path and confines acoustic energy within the electrode gap.
Zi‐Dong Zhang   +7 more
wiley   +1 more source

Presentación QS World University Rankings : Latin America, ante la Duodécima Reunión Extraordinaria del Consejo Ejecutivo de la UDUAL

open access: yes, 2022
12 diapositivas en PDF.Presentación del listado de las mejores universidades de la región "World University Rankings : Latin America" por Leigh Kamolins, director de Evaluación y Analíticas de la la firma británica QS Quacquarelli Symonds, University ...
Archivo UDUALC
core  

Konsep pendidikan akal dalam Al-Qur’an: studi QS. al-Ra’d: 19, QS. al-Baqarah: 164 dan QS. al-Maidah: 100 [PDF]

open access: yes, 2021
Skripsi ini membahas konsep pendidikan akal yang terdapat di dalam QS. al-Ra’d: 19, QS. al-Baqarah: 164 dan QS. al-Ma’idah: 100. Kajian penelitian ini dilatarbelakangi oleh spirit untuk menemukan konsep pendidikan akal sebagaimana yang termaktub di dalam
Umariyah, Tutik
core  

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

open access: yesAdvanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin   +9 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu   +8 more
wiley   +1 more source

Giant Bulk Photovoltaic Effect in Two‐Dimensional Topological Ferroelectric Semimetal

open access: yesAdvanced Science, EarlyView.
ABSTRACT Ferroelectric (FE) metals have attracted growing interest because they combine ferroelectricity with metallic behavior and enable polarization‐controlled band topology near the Fermi level. However, the number of known ferroelectric metals is still limited.
Jianhua Wang   +8 more
wiley   +1 more source

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