Results 71 to 80 of about 76,897 (289)
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Crisis Management for International Offices
, 2020 Managing the impacts and potential risks of a crisis is at the forefront of many international officers’ minds. The coronavirus outbreak has already affected more than 130 countries and impacted over 80% of the world’s student population.
QS
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Raih penarafan QS 5 Stars untuk pembelajaran dalam talian [PDF]
, 2020 Kuala Lumpur: Taylor's Universiti meningkatkan pencapaiannya dengan mendahului universiti swasta lain apabila melonjak sebanyak 135 tempat pada kedudukan ke-379 menerusi penarafan Quacquarelli Symonds (QS) World University Rankings 2021, baru-baru ...
Siti Nur Azwin, Zulkapri
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Advanced Science, EarlyView.An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu +8 more
wiley +1 more source
Control of bacterial quorum threshold for metabolic homeostasis and cooperativity
Microbiology SpectrumMany Proteobacteria employ an acyl-homoserine lactone (AHL)-mediated quorum sensing (QS) system to control diverse social behaviors in a cell density-dependent manner. Various QS modulation mechanisms securing QS initiation at high cell density have been
Eunhye Goo, Ingyu Hwang
doaj +1 more source
Diverse Landscape of Tunable Magnetic, Topological, and Ferroelectric States in 2D Ti3Se3Te2
Advanced Science, EarlyView.Ti3Se3Te2 emerges as a multifunctional 2D van der Waals platform. The monolayer is a dynamically stable ferromagnetic quantum anomalous Hall insulator. In bilayers, two stacking configurations yield distinct phases: AA‐stacking hosts an altermagnetic quantum spin Hall insulator, while AA′‐stacking exhibits three‐state in‐plane ferroelectricity ...
Jiangtao Yu +5 more
wiley +1 more source
Brazilian Journal of BiologyThe study of litter decomposition and nutrient cycling is essential to know native forests structure and functioning. Mathematical models can help to understand the local and temporal litter fall variations and their environmental variables relationships.
FP. Nunes, QS. Garcia
doaj +1 more source
強震動の二重スペクトル比を用いたQs値の空間的変動の推定 [PDF]
, 2002 2つの地震の際の2つの観測点での強震記録の二重スペクトル比を用いることによって，ある特定の経路に沿って伝播するS波の，単位行程あたりの平均的な減衰の大きさを調べることができる．観測点の組合せを変えると伝播経路が変わるため，減衰の大きさも変化する．いろいろな経路に沿って求められた減衰の大きさを満足するように，S波の減衰に関するQs値の空間的な変動を推定することが出来る．愛知県をほぼ東西に横切る地殻内でのQs値は，中央部分で大きく，両側で小さい．東側のQs値の小さい領域には中央構造線(M.T.L ...
池谷, 太輔, 泉谷, 恭男
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Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source