Results 61 to 70 of about 57,588 (165)
Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between
Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha +5 more
wiley +1 more source
Genetic programming in data mining for drug discovery [PDF]
, 2004 Genetic programming (GP) is used to extract from rat oral bioavailability (OB) measurements simple, interpretable and predictive QSAR models which both generalise to rats and to marketed drugs in humans. Receiver Operating Characteristics (ROC) curves
Barrett, S.J., Langdon, W.B.
core +2 more sources
PROTEOMICS, Volume 26, Issue 5, Page 98-111, May 2026.ABSTRACT It is widely established that the layers of proteins bound to the surface of nanoparticles (NPs), also known as the protein corona, critically influence their behavior in biological environments. Despite numerous proteomics studies performed in different NP‐corona systems, the impact of proteomic sample preparation methods on corona profiling ...
Asia Saorin +4 more
wiley +1 more source
Pest Management Science, Volume 82, Issue 5, Page 4632-4647, May 2026.XXXX Abstract BACKGROUND Spodoptera frugiperda, commonly known as the fall armyworm, is a highly economically significant pest that affects various crops, resulting in substantial losses in productivity. Managing this pest primarily relies on chemical insecticides; however, the repeated development of resistance to these chemicals has rendered them ...
Daniel Guimarães Silva Paulo +9 more
wiley +1 more source
Geophysical Research Letters, Volume 53, Issue 8, 28 April 2026.Abstract Hovmöller plots of upper‐tropospheric local (Rossby) wave activity (LWA) show that the subtropics of the North Pacific/Atlantic basins are relatively wave‐free in the upstream and wavier in the downstream of quasi‐stationary atmospheric rivers (QSARs).
Hung‐I. Lee, Noboru Nakamura
wiley +1 more source
Understanding the Evolution of Global Atmospheric Rivers With a Vapor Kinetic Energy Framework
Geophysical Research Letters, Volume 53, Issue 7, 16 April 2026.Abstract Atmospheric rivers (ARs) often cause damaging winds, rainfall, and floods. However, the physical mechanisms governing their evolution remain poorly understood. To close this gap, we perform a global Vapor Kinetic Energy (VKE) budget analysis. Using two formulations of VKE, we show that ARs are governed by similar mechanisms regardless of ocean
Aidi Zhang +3 more
wiley +1 more source
Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits
ChemMedChem, Volume 21, Issue 7, 14 April 2026.A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça +14 more
wiley +1 more source
Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]
, 2019 BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes) +9 more
core
Relating Methanogen Community Structure and Anaerobic Digester Function [PDF]
, 2015 Much remains unknown about the relationships between microbial community structure and anaerobic digester function. However, knowledge of links between community structure and function, such as specific methanogenic activity (SMA) and COD removal rate ...
Bocher, Benjamin T.W. +4 more
core +1 more source
In silico generation of novel, drug-like chemical matter using the LSTM neural network
, 2017 The exploration of novel chemical spaces is one of the most important tasks of cheminformatics when supporting the drug discovery process. Properly designed and trained deep neural networks can provide a viable alternative to brute-force de novo ...
Ertl, Peter +3 more
core