Results 1 to 10 of about 1,966,672 (115)

A Study on the Diurnal Variation of Ventricular Repolarization Parameters in Patients with Obstructive Sleep Apnea [PDF]

Zhongguo quanke yixue, 2022
BackgroundObstructive sleep apnea hypopnea syndrome (OSAHS) is a common sleep breathing disorder. More and more studies have shown that OSAHS has a significant correlation with cardiovascular disease.
YANG Beibei, JIANG Junguang, SHI Jiang, ZHANG Yang
doaj   +1 more source

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Nature Communications, 2022
The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT interval, respectively. QT interval abnormalities are associated with potentially fatal ventricular
William J. Young, N. Lahrouchi, A. Isaacs, T. Duong, L. Foco, F. Ahmed, J. Brody, Reem Salman, R. Noordam, J. Benjamins, J. Haessler, L. Lyytikäinen, Linda Repetto, M. P. Concas, M. E. van den Berg, S. Weiss, Antoine R Baldassari, T. Bartz, J. Cook, Daniel S. Evans, Rebecca Freudling, Oliver Hines, J. Isaksen, Honghuang Lin, H. Mei, A. Moscati, M. Müller-Nurasyid, Casia Nursyifa, Yong Qian, Anne Richmond, C. Roselli, K. Ryan, E. Tarazona-Santos, S. Thériault, S. van Duijvenboden, H. Warren, Jie Yao, Dania Raza, S. Aeschbacher, G. Ahlberg, Á. Alonso, L. Andreasen, J. Bis, E. Boerwinkle, A. Campbell, E. Catamo, M. Cocca, M. Cutler, D. Darbar, A. De Grandi, A. de Luca, Jun Ding, C. Ellervik, P. Ellinor, S. Felix, P. Froguel, C. Fuchsberger, Martin Gögele, C. Graff, M. Graff, Xiuqing Guo, T. Hansen, S. Heckbert, Paul L. Huang, H. Huikuri, N. Hutri-Kähönen, M. A. Ikram, R. Jackson, J. Junttila, M. Kavousi, J. Kors, T. P. Leal, R. Lemaitre, Henry J. Lin, L. Lind, A. Linneberg, Simin Liu, P. Macfarlane, M. Mangino, T. Meitinger, Massimo Mezzavilla, Pashupati P. Mishra, Rebecca N. Mitchell, N. Mononen, M. Montasser, A. Morrison, M. Nauck, V. Nauffal, P. Navarro, K. Nikus, G. Paré, K. Patton, G. Pelliccione, A. Pittman, D. Porteous, P. Pramstaller, Michael H. Preuss, O. Raitakari, A. Reiner, A. L. Ribeiro, K. Rice, L. Risch, D. Schlessinger, U. Schotten, C. Schurmann, Xia Shen, M. B. Shoemaker, G. Sinagra, Moritz F. Sinner, E. Soliman, M. Stoll, K. Strauch, K. Tarasov, K. Taylor, A. Tinker, S. Trompet, A. Uitterlinden, U. Völker, H. Völzke, M. Waldenberger, L. Weng, E. Whitsel, James G. Wilson, C. Avery, D. Conen, A. Correa, F. Cucca, M. Dörr, S. Gharib, G. Girotto, N. Grarup, C. Hayward, Y. Jamshidi, M. Järvelin, J. Jukema, S. Kääb, M. Kähönen, J. Kanters, C. Kooperberg, T. Lehtimäki, M. F. Lima-Costa, Yongmei Liu, R. Loos, S. Lubitz, D. Mook-Kanamori, A. Morris, J. O’Connell, M. Olesen, M. Orini, S. Padmanabhan, C. Pattaro, Annette Peters, B. Psaty, J. Rotter, B. Stricker, P. van der Harst, C. V. van Duijn, N. Verweij, James F. Wilson, D. Arking, J. Ramírez, P. Lambiase, N. Sotoodehnia, Borbála Mifsud, C. Newton‐Cheh, P. Munroe   +165 more
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Serial electrocardiogram recordings revealed a high prevalence of QT interval prolongation in patients with tuberculosis receiving fluoroquinolones

Journal of the Formosan Medical Association, 2023
Background: Fluoroquinolones, crucial components of treatment regimens for drug-resistant tuberculosis (TB), are associated with QT interval prolongation and risks of fatal cardiac arrhythmias. However, few studies have explored dynamic changes in the QT
Ke-Shiuan Ju, Ren-Guey Lee, Hsien-Chun Lin, Jin-Hua Chen, Bi-Fang Hsu, Jann-Yuan Wang, Nguyen Van Dong, Ming-Chih Yu, Chih-Hsin Lee   +8 more
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Measurement of the QT interval using the Apple Watch

Scientific Reports, 2021
The inherited and acquired long QT is a risk marker for potential serious cardiac arrhythmias and sudden cardiac death. Smartwatches are becoming more popular and are increasingly used for monitoring human health.
C. Spaccarotella, S. Migliarino, A. Mongiardo, J. Sabatino, G. Santarpia, S. De Rosa, A. Curcio, C. Indolfi   +7 more
semanticscholar   +1 more source

Risk of QT Interval Prolongation Associated With Use of Hydroxychloroquine With or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19).

JAMA cardiology, 2020
Importance Administration of hydroxychloroquine with or without azithromycin for the treatment of coronavirus disease 2019 (COVID-19)-associated pneumonia carries increased risk of corrected QT (QTc) prolongation and cardiac arrhythmias.
Nicholas J. Mercuro, C. Yen, David Shim, T. Maher, Christopher M. McCoy, P. Zimetbaum, H. Gold   +6 more
semanticscholar   +1 more source

Corrected QT interval and QT dispersion in temporal lobe epilepsy

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Cardiac arrhythmias are expected among patients with epilepsy due to the effect of anti-epileptic drugs. Temporal lobe epilepsy also causes autonomic seizures that may affect heart rhythm.
Maram Samy Nasef, Ahmed Abdelmonem Gaber, Yousry Aboelnaga Abdelhamid, Islam Bastawy, Salem Taha Abdelhady, Mona Mokhtar Wahid el din   +5 more
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Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection

Circulation: Arrhythmia and Electrophysiology, 2020
Background: The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is responsible for the global coronavirus disease 2019 pandemic.
Moussa Saleh, James K. Gabriels, David Chang, Beom Soo Kim, Amtul Mansoor, Eitezaz Mahmood, P. Makker, Haisam Ismail, B. Goldner, J. Willner, S. Beldner, R. Mitra, R. John, J. Chinitz, Nicholas Skipitaris, Stavros E. Mountantonakis, L. Epstein   +16 more
semanticscholar   +1 more source

The QT Interval in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine/Azithromycin

medRxiv, 2020
We report the change in the QT interval in 84 adult patients with SARS-CoV-2 infection treated with Hydroxychloroquine/Azithromycin combination. QTc prolonged maximally from baseline between days 3 and 4.
E. Chorin, Matthew Dai, E. Shulman, L. Wadhwani, R. B. Cohen, Chirag R. Barbhaiya, A. Aizer, Douglas S. Holmes, S. Bernstein, Michael Soinelli, David S. Park, L. Chinitz, L. Jankelosn   +12 more
semanticscholar   +1 more source

QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]

PLoS ONE, 2014
The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii, Yuji Ozeki, Hiroaki Okayasu, Yumiko Takano, Takahiro Shinozaki, Hiroaki Hori, Masami Orui, Minoru Horie, Hiroshi Kunugi, Kazutaka Shimoda   +9 more
doaj   +1 more source

QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin

Heart Rhythm, 2020
Background There is no known effective therapy for patients with COVID-19. Initial reports suggesting the potential benefit of Hydroxychloroquine/Azithromycin (HY/AZ) have resulted in massive adoption of this combination worldwide ...
E. Chorin, Lalit Wadhwani, S. Magnani, Matthew Dai, E. Shulman, C. Nadeau-Routhier, R. Knotts, Roi Bar-Cohen, Edward V. Kogan, Chirag R. Barbhaiya, A. Aizer, Douglas S. Holmes, S. Bernstein, Michael A. Spinelli, David S. Park, Carugo Stefano, L. Chinitz, Lior Jankelson   +17 more
semanticscholar   +1 more source