The Measurement of the QT Interval [PDF]
Current Cardiology Reviews, 2014 The evaluation of every electrocardiogram should also include an effort to interpret the QT interval to assess the risk of malignant arrhythmias and sudden death associated with an aberrant QT interval. The QT interval is measured from the beginning of the QRS complex to the end of the T-wave, and should be corrected for heart rate to enable comparison
Postema, Pieter G., Wilde, Arthur A. M.
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Journal of Human Hypertension, 2000 QT interval has been determined in 103 monozygotic (MZ) and 198 dizygotic (DZ) female twins. Mean values of corrected QT (QTc) were almost identical for both groups at 413 ms (MZ) and 412 ms (DZ). There was a significant age and environmental effect on QT interval. Heritability explained about 25% of the variation in QT.
N, Carter +6 more
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Prolonged QT interval: A tricky diagnosis? [PDF]
, 1997 Prolonged heart-rate adjusted QT intervals on the electrocardiogram (ECG) are associated with an increased risk far coronary heart disease and sudden death. However, the diagnosis of the prolonged QT interval is hampered by lack of standards.
Bemmel, J.H. (Jan) van +6 more
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Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer. [PDF]
, 2018 The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in ...
Durairaj, Chandrasekar +12 more
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A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations:the EUROSPAN project [PDF]
, 2009 We set out to identify common genetic determinants of the length of the RR and QT intervals in 2325 individuals from isolated European populations.We analyzed the heart rate at rest, measured as the RR interval, and the length of the corrected QT ...
, +20 more
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QT Interval Changes in Moderate and Severe Brain Injuries [PDF]
, 2012 Backgrounds: Traumatic brain injuries are common mortality causes in many countries. Electrocardiogram (ECG) changes after brain injuries are known, and among them alteration of QT interval is common.
Abbasi Fard, Salman. +4 more
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Heritability of Tpeak-Tend interval and T-wave amplitude: a twin study [PDF]
, 2011 Background— Tpeak-Tend interval (TpTe) and T-wave amplitude (Tamp) carry diagnostic and prognostic information regarding cardiac morbidity and mortality. Heart rate and QT interval are known to be heritable traits.
Budtz-Jørgensen, Esben +4 more
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QT Indexes in Cirrhotic Patients: Relationship with Clinical Variables and Potential Diagnostic Predictive Value. [PDF]
, 2015 BACKGROUND AND AIMS: A wide spectrum of cardiovascular changes characterizes cirrhosis, ranging from subclinical alterations to hyperkinetic syndrome.
BUTTA', Carmelo +11 more
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Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies [PDF]
, 2012 To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS ...
Arking, Dan E. +35 more
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Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]
, 2020 Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Friedman, Ari B. +2 more
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