Results 11 to 20 of about 1,993,809 (355)

Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection

Circulation: Arrhythmia and Electrophysiology, 2020
Background: The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is responsible for the global coronavirus disease 2019 pandemic.
Moussa Saleh, James K. Gabriels, David Chang, Beom Soo Kim, Amtul Mansoor, Eitezaz Mahmood, P. Makker, Haisam Ismail, B. Goldner, J. Willner, S. Beldner, R. Mitra, R. John, J. Chinitz, Nicholas Skipitaris, Stavros E. Mountantonakis, L. Epstein   +16 more
semanticscholar   +1 more source

The QT Interval in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine/Azithromycin

medRxiv, 2020
We report the change in the QT interval in 84 adult patients with SARS-CoV-2 infection treated with Hydroxychloroquine/Azithromycin combination. QTc prolonged maximally from baseline between days 3 and 4.
E. Chorin, Matthew Dai, E. Shulman, L. Wadhwani, R. B. Cohen, Chirag R. Barbhaiya, A. Aizer, Douglas S. Holmes, S. Bernstein, Michael Soinelli, David S. Park, L. Chinitz, L. Jankelosn   +12 more
semanticscholar   +1 more source

QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]

PLoS ONE, 2014
The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii, Yuji Ozeki, Hiroaki Okayasu, Yumiko Takano, Takahiro Shinozaki, Hiroaki Hori, Masami Orui, Minoru Horie, Hiroshi Kunugi, Kazutaka Shimoda   +9 more
doaj   +1 more source

QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin

Heart Rhythm, 2020
Background There is no known effective therapy for patients with COVID-19. Initial reports suggesting the potential benefit of Hydroxychloroquine/Azithromycin (HY/AZ) have resulted in massive adoption of this combination worldwide ...
E. Chorin, Lalit Wadhwani, S. Magnani, Matthew Dai, E. Shulman, C. Nadeau-Routhier, R. Knotts, Roi Bar-Cohen, Edward V. Kogan, Chirag R. Barbhaiya, A. Aizer, Douglas S. Holmes, S. Bernstein, Michael A. Spinelli, David S. Park, Carugo Stefano, L. Chinitz, Lior Jankelson   +17 more
semanticscholar   +1 more source

QT interval in twins [PDF]

Journal of Human Hypertension, 2000
QT interval has been determined in 103 monozygotic (MZ) and 198 dizygotic (DZ) female twins. Mean values of corrected QT (QTc) were almost identical for both groups at 413 ms (MZ) and 412 ms (DZ). There was a significant age and environmental effect on QT interval. Heritability explained about 25% of the variation in QT.
R Saumarez, Harold Snieder, C Varma, L Antoniades, Nicholas D. Carter, Steve Jeffery, Tim D. Spector   +6 more
openaire   +3 more sources

CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION

Рациональная фармакотерапия в кардиологии, 2015
Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired.
N. V. Furman, S. S. Shmatova
doaj   +3 more sources

Experience With Hydroxychloroquine and Azithromycin in the Coronavirus Disease 2019 Pandemic: Implications for QT Interval Monitoring

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Despite a lack of clinical evidence, hydroxychloroquine and azithromycin are being administered widely to patients with verified or suspected coronavirus disease 2019 (COVID‐19).
A. Ramireddy, H. Chugh, K. Reinier, J. Ebinger, E. Park, M. Thompson, E. Cingolani, Susan Cheng, E. Marbán, C. Albert, S. Chugh   +10 more
semanticscholar   +1 more source

Short-Term Beat-to-Beat QT Variability Appears Influenced More Strongly by Recording Quality Than by Beat-to-Beat RR Variability

Frontiers in Physiology, 2022
Increases in beat-to-beat variability of electrocardiographic QT interval duration have repeatedly been associated with increased risk of cardiovascular events and complications.
Ondřej Toman, Ondřej Toman, Katerina Hnatkova, Martina Šišáková, Martina Šišáková, Peter Smetana, Katharina M. Huster, Petra Barthel, Tomáš Novotný, Tomáš Novotný, Irena Andršová, Irena Andršová, Georg Schmidt, Marek Malik, Marek Malik   +14 more
doaj   +1 more source

QT interval

The Egyptian Heart Journal, 2014
Background: Occupational factors are likely to contribute to increased cardiovascular disease risk among emergency medical responders (EMR). The aim of this study was to clarify whether EMR stressful Job and their prolonged exposure to work stress are ...
E. El-safty, Ayman A. Abdelaziz, E. Khashaba, I. Al-Wehedy, M. El sheref, M. Neamatallah   +5 more
doaj   +1 more source

METHODOLOGICAL APPROACHES TO MEASURING AND ESTIMATING THE DURATION OF QT INTERVAL OF A STANDARD ELECTROCARDIOGRAM

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019
Interpretation of each electrocardiogram should include measurement and evaluation of the QT interval, because both an increase and a decrease in its duration are associated with a risk of polymorphic ventricular tachycardia and sudden cardiac death ...
Kalatsei L. V., Snezhitskiy V. A.
doaj   +1 more source