Results 41 to 50 of about 1,993,809 (355)

Parameters of ventricular repolarization in patients with autoimmune hepatitis

open access: yesTürk Kardiyoloji Derneği Arşivi, 2017
Objective: Autoimmune hepatitis (AIH) is a liver disorder that affects both children and adults. It is characterized by inflammatory liver histology, elevated transaminase level, circulating nonorgan-specific autoantibodies, and increased level of ...
Burak Açar   +11 more
doaj   +1 more source

Prevalence of QTc interval prolongation and its associated risk factors among psychiatric patients: a prospective observational study

open access: yesBMC Psychiatry, 2020
Background QT interval prolongation is a growing concern worldwide, posing psychiatric patients to life-threatening fatal arrhythmias i.e., torsade de pointes.
Zahid Ali   +5 more
doaj   +1 more source

Thoracic epidural analgesia prolongs postoperative QT interval on electrocardiogram in major non-cardiac surgery: a randomized comparison and a prospective cohort analysis

open access: yesFrontiers in Pharmacology, 2023
Introduction: Prolongation of QT interval on electrocardiogram can be associated with perioperative lethal arrhythmia. Epidural analgesia is a commonly used modality to relieve surgical pain by blocking sensory nerves, which also blocks the autonomic ...
Kotaro Hori   +7 more
doaj   +1 more source

Dynamics of QT Interval in a Patient With Long QT Syndrome and a Normal QT Interval

open access: yesJapanese Circulation Journal, 1998
A case report of a 15-year-old girl who experienced syncope and torsades de pointes is presented. The girl had a normal QT interval (QTc=0.37 sec) on the resting electrocardiogram (ECG). Infusion of isoproterenol induced QT prolongation (QTc=0.62 sec) and frequent occurrence of multiform ventricular premature beats. Her Holter ECG showed a prolongation
Morio Ito   +8 more
openaire   +4 more sources

The effects of peritoneal dialysis on QT interval in ESRD patients

open access: yesBMC Nephrology, 2022
Background Patients with chronic kidney disease (CKD) are at a high risk of fatal arrhythmias. The extended corrected QT (QTc) interval is a hallmark of ventricular arrhythmias and sudden cardiac death.
Wenjing Zhang   +4 more
doaj   +1 more source

Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes

open access: yesActa Diabetologica, 2016
AimsProlonged QT interval is associated with cardiac arrhythmias and sudden death. The present study determined the prevalence of prolonged QT interval and QT dispersion and defined their clinical and metabolic predictors in patients with type 2 diabetes.
V. Ninkovic   +10 more
semanticscholar   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Identification of Patients At-Risk of QT Interval Prolongation during Medication Reviews: A Missed Opportunity?

open access: yesJournal of Clinical Medicine, 2018
The prolongation of the QT interval is a relatively rare but serious adverse drug reaction. It can lead to torsade de pointes, which is potentially life-threatening.
V. Buss   +4 more
semanticscholar   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation

open access: yesJournal of Pharmacological Sciences, 2005
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys.
Kentaro Ando   +12 more
doaj   +1 more source

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