Results 61 to 70 of about 1,993,809 (355)

Co-Prescription of QT-Interval Prolonging Drugs: An Analysis in a Large Cohort of Geriatric Patients

PLoS ONE, 2016
Background Drug-induced QT-interval prolongation is associated with occurrence of potentially fatal Torsades de Pointes arrhythmias (TdP). So far, data regarding the overall burden of QT-interval prolonging drugs (QT-drugs) in geriatric patients are ...
S. Schächtele, T. Tümena, K. Gassmann, M. Fromm, R. Maas   +4 more
semanticscholar   +1 more source

Drink, Drugs, and the QT Interval [PDF]

Clinical Cardiology, 2010
AbstractThe effects of several prescription and illicitly‐used drugs on electrocardiographic repolarization are well documented, most frequently manifested as prolongation of the corrected QT (QTc) interval. The combination of multiple repolarization‐modulating drugs taken in high dosage can occasionally lead to extreme abnormalities of the QTc ...
Henry J. Dargie, Charles Angus Murphy, Robin A.P. Weir, Colin J. Petrie   +3 more
openaire   +3 more sources

Non‐PFAS‐Based Magnetic Polymer Sorbents for Efficient Removal of Perfluorinated Compounds from Landfill Leachate

Advanced Materials, EarlyView.
Magnetic polymer sorbents featuring non‐per‐ and polyfluoroalkyl substances (non‐PFAS)‐based fluorinated and cationic groups enable selective and efficient removal of multiple PFAS from complex landfill leachate. By optimizing functional group balance and polymer design, the sorbents achieve >90% removal, excellent reusability, and outperform ...
Xiao Tan, Zhuojing Yang, Zhou Chen, Yutong Zhu, Chunrong Yu, Yiqing Wang, Kehan Liu, Pradeep Dewapriya, Xuemei Li, Zicheng Su, Marcus J. Giansiracusa, Colette Boskovic, Biao Wang, Kevin V. Thomas, Cheng Zhang   +14 more
wiley   +1 more source

Multimodal Luminescence from LaAlO3:Eu3+ via Trap Modulation for High‐Temperature Applications

Advanced Photonics Research, EarlyView.
LaAlO3:Eu3+ (LAO:E) phosphor exhibiting multimode luminescence enabled by multilevel traps spanning shallow to deep states is reported. These traps ensure controlled charge storage and release at room and elevated temperatures. Experimental studies and theoretical calculations reveal the trapping–detrapping mechanism, highlighting LAO:E as a promising ...
Abdulelah Alolayan, Nimai Pathak, Kawsar Ali, Yuanbing Mao   +3 more
wiley   +1 more source

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

Therapeutic Advances in Psychopharmacology, 2022
Background: A prolonged electrocardiogram (ECG) QT interval is associated with cardiac events and increased mortality. Antipsychotics can prolong the QT interval.
Teodora Andric, Karl Winckel, Timothy David Tanzer, Samantha Hollingworth, Lesley Smith, Katherine Isoardi, Olivier Tan, Dan Siskind   +7 more
doaj   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Severity and multiplicity of microvascular complications are associated with QT interval prolongation in patients with type 2 diabetes

Journal of Diabetes Investigation, 2017
A prolonged QT interval plays a causal role in life‐threatening arrhythmia, and becomes a risk factor for sudden cardiac death. Here, we assessed the association between microvascular complications and the QT interval in patients with type 2 diabetes.
Shunsuke Kobayashi, Mototsugu Nagao, A. Asai, I. Fukuda, S. Oikawa, H. Sugihara   +5 more
semanticscholar   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

QTc interval measurement in patients with right bundle branch block: A practical method

Annals of Noninvasive Electrocardiology, 2023
Background and Aim Prolonging the QT interval in the right bundle branch block (RBBB) can create challenges for electrophysiologists in estimating repolarization time and eliminating the effect of depolarization changes on QT interval.
Abolfath Alizadeh, Mohammad Amin Shahrbaf, Mohammadrafie Khorgami, Mahboubeh Zeighami, Ala Keikhavani, Hamid Mokhtari Torshizi, Zahra Teimouri‐jervekani   +6 more
doaj   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source