Results 61 to 70 of about 2,134,558 (310)

Heritability of Tpeak-Tend interval and T-wave amplitude: a twin study [PDF]

, 2011
Background— Tpeak-Tend interval (TpTe) and T-wave amplitude (Tamp) carry diagnostic and prognostic information regarding cardiac morbidity and mortality. Heart rate and QT interval are known to be heritable traits.
Budtz-Jørgensen, Esben, Haarmark, Christian, Kanters, Jørgen K., Kyvik, Kirsten O, Vedel-Larsen, Esben   +4 more
core   +1 more source

Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes

Acta Diabetologica, 2016
AimsProlonged QT interval is associated with cardiac arrhythmias and sudden death. The present study determined the prevalence of prolonged QT interval and QT dispersion and defined their clinical and metabolic predictors in patients with type 2 diabetes.
V. Ninkovic, S. Ninkovic, V. Miloradovic, Dejan Stanojević, Marijana Babic, V. Giga, M. Dobric, M. Trenell, N. Lalic, P. Seferovic, D. Jakovljevic   +10 more
semanticscholar   +1 more source

QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation

Journal of Pharmacological Sciences, 2005
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys.
Kentaro Ando, Toshiyasu Hombo, Akihiro Kanno, Hironobu Ikeda, Masakazu Imaizumi, Noritsugu Shimizu, Kengo Sakamoto, Shin-ichi Kitani, Yoshinori Yamamoto, Shingo Hizume, Keiko Nakai, Tetsuya Kitayama, Keiji Yamamoto   +12 more
doaj   +1 more source

The effects of peritoneal dialysis on QT interval in ESRD patients

BMC Nephrology, 2022
Background Patients with chronic kidney disease (CKD) are at a high risk of fatal arrhythmias. The extended corrected QT (QTc) interval is a hallmark of ventricular arrhythmias and sudden cardiac death.
Wenjing Zhang, Yu Liang, Jia Lv, Yan Li, Jiping Sun   +4 more
doaj   +1 more source

Acute effects of coffee on QT interval in healthy subjects [PDF]

, 2011
The coronary endothelial function is recognized to have an important role in the physiology of the diastolic ventricular relaxation, a phase of the heart cycle that influences the electrocardiographic QT interval.
BUSCEMI, Silvio, Mattina, A, Tranchina, MR, VERGA, Salvatore   +3 more
core   +3 more sources

Identification of Patients At-Risk of QT Interval Prolongation during Medication Reviews: A Missed Opportunity?

Journal of Clinical Medicine, 2018
The prolongation of the QT interval is a relatively rare but serious adverse drug reaction. It can lead to torsade de pointes, which is potentially life-threatening.
V. Buss, Kayla Lee, M. Naunton, G. Peterson, S. Kosari   +4 more
semanticscholar   +1 more source

In silico investigation of a KCNQ1 mutation associated with short QT syndrome [PDF]

, 2017
Short QT syndrome (SQTS) is a rare condition characterized by abnormally ‘short’ QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death.
A El Harchi, A Mazzanti, C Antzelevitch, C Bellocq, C Giustetto, C Giustetto, C Lerche, C Moreno, C Patel, C Templin, DG Whittaker, DL Weiss, F Gaita, H Watanabe, H Zhang, I Adeniran, I Gussak, J Barhanin, J Silva, JA Nelder, K Gima, K Hong, KHWJ Tusscher, KHWJ Tusscher Ten, KHWJten Tusscher, L Priebe, L Restier, MC Sanguinetti, MJ Curtis, MP Nash, O Anttonen, P Bjerregaard, P Maury, R Schimpf, R Schimpf, R Schimpf, R Schimpf, R Schimpf, R Towart, RH Clayton, RH Keldermann, RS Duncan, S Frea, T O’Hara, Z-J Wu   +44 more
core   +4 more sources

Liver cirrhosis-effect on QT interval and cardiac autonomic nervous system activity

World Journal of Gastrointestinal Pathophysiology, 2018
AIM To examine the impact of liver cirrhosis on QT interval and cardiac autonomic neuropathy (CAN). METHODS A total of 51 patients with cirrhosis and 51 controls were examined. Standard 12-lead electrocardiogram recordings were obtained and QT as well as
Elias Tsiompanidis, S. Siakavellas, A. Tentolouris, I. Eleftheriadou, Stamatia Chorepsima, A. Manolakis, Konstantinos Oikonomou, N. Tentolouris   +7 more
semanticscholar   +1 more source

Biopolymer‐Templated Hierarchical 3D‐Structured Gold Nanoparticle/Graphene Oxide Hybrid Materials for Ultrasensitive Surface‐Enhanced Raman Scattering

Advanced Functional Materials, EarlyView.
A scalable bio‐templated approach using spray‐coating and thermal annealing fabricates cellulose nanofibril (CNF) films loaded with gold nanoparticles (Au NPs) and graphene oxide (GO) hybrids as Surface‐enhanced Raman scattering (SERS) substrates. The 3D CNF network ensures uniform Au NPs distribution, while annealing induces more hotspots, confirmed ...
Yingjian Guo, Guangjiu Pan, Suo Tu, Yusuf Bulut, Jungui Zhou, Arno Jeromin, Thomas F. Keller, Andreas Stierle, Gergely Nemeth, Ferenc Borondics, Benedikt Sochor, Sarathlal Koyiloth Vayalil, L. Daniel Söderberg, Peter Müller‐Buschbaum, Stephan V. Roth   +14 more
wiley   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source