Results 101 to 110 of about 55,959 (291)

A randomized controlled trial of the short-term effect of rosuvastatin on the corrected QT interval

Scientific Reports
Rosuvastatin can block human ether-a-go-go related gene (hERG) currents and prolong the corrected QT (QTc) interval, but this effect has not been confirmed in the population.
Lijun Zhu, Wenjun Shen, Wanying Hu, Haiwang Guan, Yanwei Wang, Conglin Wang, Jing Lin, Li Chen, Qingjun Jiang   +8 more
doaj   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Fluconazole-associated QT interval prolongation and Torsades de Pointes in a paediatric patient [PDF]

, 2021
Ayşe Ünal Yüksekgönül, İlker Ertuğrul, Tevfik Karagöz   +2 more
openalex   +1 more source

Herbaceous plant communities respond more to seasonal precipitation than cumulative drought in the hot deserts of the United States

Plant Biology, EarlyView.
Using a 4‐year drought experiment in the hot deserts of the US, we found that herbaceous plant communities were more sensitive to seasonal precipitation than to the cumulative effects of drought. Abstract The hot deserts of the southwestern United States are experiencing increased frequency, severity, and duration of drought due to anthropogenic ...
T. Ohlert, M. Patton, A. Hallmark, G. Hamilton, S. L. Collins   +4 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Tracer Test as a Tool for Optimizing the Flow Patterns and Efficiency of a Full‐Scale Drainage Water Treatment Wetland

Water and Environment Journal, EarlyView.
Tracer testing assessed hydraulics and nitrate removal in three full‐scale agricultural drainage treatment wetlands over 3.5 years (three tests). The first test showed rapid, short‐circuited flow and low residence time. After modifying the collection system, the second test increased residence time from 1 to 7 days.
Jan Kukačka, Michal Šereš, Petr Fučík, Tereza Hnátková, Adam Sochacki, Markéta Kaplická, Ljuba Zídková, Jan Vymazal   +7 more
wiley   +1 more source

Corrected QT Interval Prolongation Complicating Incoercible Vomiting in a Coronavirus Disease 2019 Patient Under Chloroquine and Azithromycin

, 2020
Houda Nassih, Karima El Fakiri, Rabiy El Qadiry, Aïcha Bourrahouat, Imane Ait Sab   +4 more
openalex   +1 more source

Drug-induced QT-interval prolongation and proarrhythmic risk in the treatment of atrial arrhythmias [PDF]

, 2007
Eduard Shantsila, Timothy Watson, Gregory Lip   +2 more
openalex   +1 more source

Use of drugs associated with QT interval prolongation at the hospital level during the start of the COVID-19 pandemic in Colombia v1 [PDF]

, 2020
Jorge Enrique Machado‐Alba, Andrés Gaviria‐Mendoza, Manuel Enrique Machado‐Duque, Luis Fernando Valladales‐Restrepo   +3 more
openalex   +1 more source

Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes

Experimental Physiology, EarlyView.
Abstract Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) have proven to be a revolutionary advance for tissue engineering, disease modelling, and drug testing and discovery. Computational modelling enables detailed electrophysiological analysis that is otherwise difficult or impossible to achieve under strictly experimental ...
Roshni Shetty, Raffi Samurkashian, Leslie Tung   +2 more
wiley   +1 more source