Results 141 to 150 of about 24,231 (256)

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery, Jacob A. Miller, Steven Poelzing, Seth H. Weinberg   +3 more
wiley   +1 more source

Assessment of QT Interval Prolongation Using Concentration-QT Modeling for Iptacopan, an Oral Complement Factor B Inhibitor, in Healthy Individuals. [PDF]

Clin Transl Sci
Kaetterer N, Kulmatycki K, Nidamarthy PK, McNamara E, Armas D, Jarugula V, Schmouder R.   +6 more
europepmc   +1 more source

QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Studies. [PDF]

Antimicrob Agents Chemother, 2023
Ali AM, Radtke KK, Hesseling AC, Winckler J, Schaaf HS, Draper HR, Solans BP, van der Laan L, Hughes J, Fourie B, Nielsen J, Garcia-Prats AJ, Savic RM.   +12 more
europepmc   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

QT interval prolongation from antipsychotics in schizophrenia and acute psychosis - A prospective study. [PDF]

Ind Psychiatry J
Saha A, Kumar A, Singh S, Somani A.
europepmc   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

QT interval prolongation in schizophrenia: A cross-sectional study from a tertiary care center in Raipur. [PDF]

Indian J Med Res
Malani M, Das S, Saha A, Kumar A, Singh S, Somani A.   +5 more
europepmc   +1 more source

Transient Acquired QT Interval Prolongation After Administration of Intravenous Ondansetron. [PDF]

CJC Open, 2022
Mao R, Wiens EJ, Elbarouni B.
europepmc   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

Corrected QT interval prolongation after ganglionated plexus ablation: myth or reality?-Authors' reply. [PDF]

Europace, 2021
Hermans BJM, Zink MD, Rosmalen FV, Crijns HJGM, Vernooy K, Postema P, Pison L, Schotten U, Delhaas T.   +8 more
europepmc   +1 more source