Results 151 to 160 of about 24,231 (256)

Extreme QT interval prolongation in Wellens syndrome. [PDF]

open access: yesEur Heart J Case Rep
Abdelmaaboud M, Margulescu AD.
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider   +3 more
wiley   +1 more source

QT-Interval Prolongation and 1-Year Cardiac Death Among Patients Undergoing Hemodialysis. [PDF]

open access: yesJACC Asia
Sasaki S   +6 more
europepmc   +1 more source

Obesity and QT interval prolongation

open access: yesJournal of the Japanese Society of Intensive Care Medicine, 2007
Iwasaki, Yu-ki, Tanaka, Keiji
openaire   +2 more sources

Quizartinib in Combination With FLAG‐IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG‐QUIDA): A PETHEMA Phase I‐II Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2258-2268, September 2026.
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal   +29 more
wiley   +1 more source

QT Interval Prolongation and Beyond [PDF]

open access: yesAnnals of Noninvasive Electrocardiology, 2006
openaire   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy