Results 161 to 170 of about 73,159 (323)

High-Throughput Assessment of Real-World Medication Effects on QT Interval Prolongation: Observational Study. [PDF]

JMIR Cardio, 2023
Yuan N, Oesterle A, Botting P, Chugh S, Albert C, Ebinger J, Ouyang D.   +6 more
europepmc   +1 more source

Solifenacin linked QT interval prolongation and torsades de pointes [PDF]

, 2017
Bray, Jonathan, Hancox, Jules
core   +1 more source

An indicator of sudden cardiac death during brief coronary occlusion: electrocardiogram QT time and the role of collaterals [PDF]

, 2017
Aims The coronary collateral circulation has a beneficial role regarding all-cause and cardiac mortality. Hitherto, the underlying mechanism has not been clarified.
de Marchi, Stefano F., Delacrétaz, Etienne, Gloekler, Steffen, Meier, Pascal, Seiler, Christian, Zbinden, Rainer   +5 more
core  

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Effects of adjunctive pimavanserin and current antipsychotic treatment on QT interval prolongation in patients with schizophrenia. [PDF]

Front Psychiatry, 2022
Bugarski-Kirola D, Nunez R, Odetalla R, Liu IY, Turner ME.   +4 more
europepmc   +1 more source

Clinical cardiac electrophysiologic evaluation of the positive inotropic agent, DPI 201-106 [PDF]

, 2017
DPI 201-106 is a new positive inotropic agent. The cardiac electrophysiology of 16 patients was studied before and during DPI 201-106 administration (loading dose of intravenous DPI 201-106, 1·8 mg kg−1 h−1 administered over 10 min, followed by a ...
BUTROUS, G. S., CAMM, A. J., DAVIES, D. W., DEBBAS, N. M. G., ERWIN, J., KELLER, H. P., LUNNON, M. W., NATHAN, A. W.   +7 more
core  

Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjects

, 2015
Dong‐Seok Yim, Taegon Hong, Seunghoon Han, Jong-Tae Lee, Sangil Jeon, Gab-Jin Park, Wan‐Su Park, Kyoung Soo Lim, Jae‐Yong Chung, Kyung-Sang Yu   +9 more
openalex   +2 more sources

A randomized, double‐blinded, placebo‐controlled study to evaluate the efficacy and safety of venlafaxine extended release in Japanese patients with generalized anxiety disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The current study investigated the superiority of anxiolytic effects of venlafaxine extended release (ER) compared with placebo and its safety and tolerability in Japanese adult outpatients with generalized anxiety disorder (GAD). Methods In this placebo‐controlled, double‐blind study, 357 eligible participants were randomized to receive ...
Tempei Otsubo, Koichiro Watanabe, Takeshi Inoue, Ataru Inagaki, Toshiaki Kikuchi, Keisuke Nomoto, Shingo Higa, Yuko Asami, Bin Sun, Kristina Marschall   +9 more
wiley   +1 more source

Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]

, 2001
Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core  

QT Interval Prolongation and Torsade de Pointes Induced by Propofol and Hypoalbuminemia

, 2010
Tadanobu Irie, Yoshiaki Kaneko, Tadashi Nakajima, Akihiro Saito, Masahiko Kurabayashi   +4 more
openalex   +2 more sources