Results 161 to 170 of about 55,959 (291)

QT interval prolongation and mortality in sepsis: a retrospective cohort study from the MIMIC-IV database. [PDF]

BMC Cardiovasc Disord
Zhang JY, Chen Y, Zhang YX, Yang BJ.
europepmc   +1 more source

Managing Drug–Drug Interactions Involving the Non‐Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou, Garrett R. Ainslie, Mengyao Li, Jean Dinh, Maciej J. Zamek‐Gliszczynski, Ping Zhao, Mary F. Paine   +6 more
wiley   +1 more source

QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]

J Pharmacokinet Pharmacodyn
Gotta V, Donner B.
europepmc   +1 more source

Heart rate-corrected QT interval prolongation is associated with decreased heart rate variability in patients with type 2 diabetes. [PDF]

Medicine (Baltimore), 2022
Cha SA.
europepmc   +1 more source

Bioelectrical Impedance Phase Angle Value and Prolongations of PR and Corrected QT Intervals in Patients Undergoing Dialysis

Masanori Shibata, Kazuaki Asai, Kojiro Nagai, Shinkichi Taniguchí   +3 more
openalex   +1 more source

Effect of QT interval prolongation on cardiac arrest following liver transplantation and derivation of a risk index [PDF]

, 2020
A. Koshy, Jefferson Ko, Omar Farouque, Shamil D. Cooray, Hui‐Chen Han, B. Cailes, Paul Gow, Laurence Weinberg, Adam Testro, H. Lim, A. Teh   +10 more
openalex   +1 more source

Suspected pro‐arrhythmic effects of flecainide and the limitations of in‐hospital short‐duration electrocardiography in detecting ventricular arrhythmia burden in a dog with dilated cardiomyopathy

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 10‐year‐old, female, spayed Pitbull mix presented for evaluation of an arrhythmia. Echocardiography revealed enlargement of all cardiac chambers and decreased left ventricular systolic function. Electrocardiography demonstrated isolated, ventricular premature complexes.
Nathan Mitchell, Tamilselvam Gunasekaran, Robert Sanders, Joanne DeSana   +3 more
wiley   +1 more source

QT Interval Prolongation in Chronic Liver Disease: A Cross-Sectional Study. [PDF]

Cureus
Venkata Harischandra T, Zulqurnain A, Irshad A, Arif M, Abdul Razzak A, Tayyab M, Rehman AU.   +6 more
europepmc   +1 more source

QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Studies. [PDF]

Antimicrob Agents Chemother, 2023
Ali AM, Radtke KK, Hesseling AC, Winckler J, Schaaf HS, Draper HR, Solans BP, van der Laan L, Hughes J, Fourie B, Nielsen J, Garcia-Prats AJ, Savic RM.   +12 more
europepmc   +1 more source

Sodium glucose co‐transporter 2 inhibitors versus dipeptidyl peptidase‐4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population‐based cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 935-945, February 2026.
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang, Pauline Reynier, Antonios Douros, Oriana H. Y. Yu, Robert W. Platt, Kristian B. Filion   +5 more
wiley   +1 more source