Results 21 to 30 of about 55,959 (291)

CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION

Рациональная фармакотерапия в кардиологии, 2015
Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired.
N. V. Furman, S. S. Shmatova
doaj   +3 more sources

Risk of QT Interval Prolongation Associated With Use of Hydroxychloroquine With or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19).

JAMA cardiology, 2020
Importance Administration of hydroxychloroquine with or without azithromycin for the treatment of coronavirus disease 2019 (COVID-19)-associated pneumonia carries increased risk of corrected QT (QTc) prolongation and cardiac arrhythmias.
Nicholas J. Mercuro, C. Yen, David Shim, T. Maher, Christopher M. McCoy, P. Zimetbaum, H. Gold   +6 more
semanticscholar   +1 more source

QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin

Heart Rhythm, 2020
Background There is no known effective therapy for patients with COVID-19. Initial reports suggesting the potential benefit of Hydroxychloroquine/Azithromycin (HY/AZ) have resulted in massive adoption of this combination worldwide ...
E. Chorin, Lalit Wadhwani, S. Magnani, Matthew Dai, E. Shulman, C. Nadeau-Routhier, R. Knotts, Roi Bar-Cohen, Edward V. Kogan, Chirag R. Barbhaiya, A. Aizer, Douglas S. Holmes, S. Bernstein, Michael A. Spinelli, David S. Park, Carugo Stefano, L. Chinitz, Lior Jankelson   +17 more
semanticscholar   +1 more source

Cancer treatment and drug-induced QT interval prolongation: A review

Consilium Medicum, 2022
Anticancer drugs can cause drug-induced prolongation of the QT interval. Prolongation of the QT interval is a known risk factor and an independent predictor of the development of life-threatening ventricular arrhythmias (polymorphic ventricular ...
Olga D. Ostroumova, Aleksey I. Kochetkov, Valeria A. De   +2 more
doaj   +1 more source

Ventricular arrhythmia in patients with prolonged QT interval during liver transplantation: two cases report [PDF]

Korean Journal of Anesthesiology, 2014
QT interval prolongation is associated with an increased risk of ventricular arrhythmia in various conditions. Cardiac electrophysiologic abnormalities including QT interval prolongation are well documented in patients with advanced liver cirrhosis.
Min-Soo Kim, Na Young Kim, Ji Eun Park, Soon Ho Nam   +3 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Torsade de pointes in liver transplantation recipient after induction of general anesthesia: a case report [PDF]

Korean Journal of Anesthesiology, 2014
Torsade de pointes (TdP) is an uncommon and specific form of polymorphic ventricular tachycardia, associated with a prolonged QT interval. Prolongation of the QT interval is the most widely recognized electrophysiological abnormality in patients with ...
Eun-Jin Chung, Yun-Seok Jeon, Hyun-Joo Kim, Kook Hyun Lee, Ji-Won Lee, Kyoung-Ah Han, Seung-Hwan Jung   +6 more
doaj   +1 more source

QT prolongation in HIV-positive patients: Review articleKey points

Indian Heart Journal, 2019
Introduction: Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. Methods: Pubmed and Google Scholar were searched for
Jing Liu, Sumit K. Shah, Indranill Basu-Ray, Julia Garcia-Diaz, Kainat Khalid, Mohammad Saeed   +5 more
doaj   +1 more source

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

THE WAYS TO ENHANCE SAFETY OF COMBINATIONS OF DRUGS PROLONGING QT INTERVAL IN THE OUT-PATIENT AND POLYCLINIC PRACTICE

Вестник анестезиологии и реаниматологии, 2018
Prolongation of QT interval is a predictor of fatal disorders of cardiac rhythm and sudden death. Side effects of medications is one of the main causes of prolonged QT interval.
E. V. Shikh, Zh. M. Sizova, A. D. Ismagilov, M. A. Vyzhigina   +3 more
doaj   +1 more source