Results 21 to 30 of about 39,180 (240)

Effectiveness of a clinical decision support system for reducing the risk of QT interval prolongation in hospitalized patients [PDF]

, 2014
BACKGROUND: We evaluated the effectiveness of a computer clinical decision support system (CDSS) for reducing the risk of QT interval prolongation in hospitalized patients.
Jaynes, Heather A., Kingery, Joanna R., Kovacs, Richard J., Mourad, Noha A., Overholser, Brian R., Tisdale, James E., Trujillo, Tate N.   +6 more
core   +1 more source

Prolonged QT interval in bulimia nervosa [PDF]

BMJ Case Reports, 2011
A 39-year-old woman with an unremarkable history presented to the emergency department with three episodes of collapse. Each episode was witnessed by her son who described a loss of consciousness followed by rapid and complete recovery. The patient appeared well and examination was unremarkable.
Ryan, Buchanan, Joseph, Ngwira, Khaled, Amsha   +2 more
openaire   +2 more sources

Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer. [PDF]

, 2018
The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in ...
Durairaj, Chandrasekar, Ettl, Johannes, Finn, Richard S, Gauthier, Eric R, Hoffman, Justin T, Huang, Xin, Joy, Anil A, Lu, Dongrui R, Rugo, Hope S, Ruiz-Garcia, Ana, Wang, Diane D, Wilner, Keith D, Zheng, Jenny   +12 more
core   +2 more sources

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

Methadone and Corrected QT Prolongation in Pain and Palliative Care Patients: A Case–Control Study [PDF]

, 2017
Background: Methadone (ME) is commonly used in pain and palliative care (PPC) patients with refractory pain or intolerable opioid adverse effects (AEs).
Brown, Jack, Hutchinson, David, Juba, Katherine, Khadem, Tina M.   +3 more
core   +2 more sources

Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]

, 2020
Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Friedman, Ari B., Rischall, Megan L., Smith, Stephen W.   +2 more
core  

Solifenacin linked QT interval prolongation and torsades de pointes [PDF]

, 2017
[no ...
Bray, Jonathan, Hancox, Jules
core   +2 more sources

Predictive Analytics for Identification of Patients at Risk for QT Interval Prolongation – A Systematic Review [PDF]

, 2018
Prolongation of the heart rate‐corrected QT (QTc) interval increases the risk for torsades de pointes (TdP), a potentially fatal arrhythmia. The likelihood of TdP is higher in patients with risk factors, which include female sex, older age, heart failure
Muensterman, Elena Tomaselli, Tisdale, James E.   +1 more
core   +1 more source

QT Interval Changes in Moderate and Severe Brain Injuries [PDF]

, 2012
Backgrounds: Traumatic brain injuries are common mortality causes in many countries. Electrocardiogram (ECG) changes after brain injuries are known, and among them alteration of QT interval is common.
Abbasi Fard, Salman., Abrishamkar, Saied., Irii, Abdol_Razagh., Momeni, Ali., Rohanizadegan, Mersedeh.   +4 more
core   +1 more source

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate, A Clarke, A Pariente, AK Chung, Ariola Koci, B Darpo, BJ Drew, C Meyer-Massetti, DM Roden, DW Hough, E Poluzzi, E Poluzzi, E Poluzzi, E Raschi, E Raschi, Edoardo Spina, Elijah R. Behr, Elisabetta Poluzzi, Emanuel Raschi, EP Puijenbroek van, ER Behr, F Ponti De, F Ponti De, F Rani, Fabrizio De Ponti, GC Alexander, GK Isbister, H Verdoux, J Nielsen, J Papay, K Jolly, K Titier, LC Wittkampf, LS Schneider, Miriam Sturkenboom, NP Tatonetti, P Kannankeril, P Manu, P Vigneault, RC Owens Jr, RR Shah, S Dhillon, S Hennessy, S Kongsamut, S Leucht, SM Straus, Ugo Moretti, W Crumb, W Crumb, WA Ray, WA Ray, WJ Crumb Jr, WP Stephenson, Y Suzuki   +53 more
core   +4 more sources