Results 41 to 50 of about 55,959 (291)

Association between C-reactive protein, corrected QT interval and presence of QT prolongation in hypertensive patients

Kaohsiung Journal of Medical Sciences, 2014
C-reactive protein (CRP) and corrected QT (QTc) interval are predictors of cardiovascular disease. Whether CRP is associated with QTc interval and QT prolongation is unknown in hypertensive patients.
Kai-Ting Chang, Hsu-Shien Shu, Chun-Yuan Chu, Wen-Hsien Lee, Po-Chao Hsu, Ho-Ming Su, Tsung-Hsien Lin, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu   +9 more
doaj   +1 more source

Scoping review: QT interval prolongation in regimen containing bedaquiline and delamanid in patients with drug-resistant tuberculosis

International Journal of Mycobacteriology, 2022
Background: A regimen containing bedaquiline–delamanid is recommended in management of drug-resistant tuberculosis (DR TB) to increase a success rate.
Oki Nugraha Putra, Yulistiani Yulistiani, Soedarsono Soedarsono   +2 more
doaj   +1 more source

The Effects of Trimetazidine on QT-interval Prolongation and Cardiac Hypertrophy in Diabetic Rats

Arquivos Brasileiros de Cardiologia, 2019
Background Trimetazidine (TMZ) is an anti-ischemic drug. In spite of its protective effects on cardiovascular system, there is no scientific study on the usefulness of TMZ treatment for prolonged QT interval and cardiac hypertrophy induced by diabetes ...
Fatemeh Ramezani-Aliakbari, M. Badavi, M. Dianat, S. Mard, A. Ahangarpour   +4 more
semanticscholar   +1 more source

Identification of Patients At-Risk of QT Interval Prolongation during Medication Reviews: A Missed Opportunity?

Journal of Clinical Medicine, 2018
The prolongation of the QT interval is a relatively rare but serious adverse drug reaction. It can lead to torsade de pointes, which is potentially life-threatening.
V. Buss, Kayla Lee, M. Naunton, G. Peterson, S. Kosari   +4 more
semanticscholar   +1 more source

QT interval prolongation after sertraline overdose: a case report

BMC Emergency Medicine, 2005
Background Selective serotonin reuptake inhibitors (SSRIs) are the most common antidepressants used in first-world countries and are generally well tolerated.
Holman Nicole D, van Dijk Tonnis H, de Boer Rudolf A, van Melle Joost P   +3 more
doaj   +1 more source

Drug-induced QT interval prolongation in cancer patients

Oncology Reviews, 2011
Cancer patients are at an increased risk for QT interval prolongation and subsequent potentially fatal Torsade de pointes tachycardia due to the multiple drugs used for treatment of malignancies and the associated symptoms and complications.
Torben K. Becker, Sai-Ching J. Yeung
doaj   +1 more source

Predictive Analytics for Identification of Patients at Risk for QT Interval Prolongation: A Systematic Review

Pharmacotherapy, 2018
Prolongation of the heart rate–corrected QT (QTc) interval increases the risk for torsade de pointes (TdP), a potentially fatal arrhythmia. The likelihood of TdP is higher in patients with risk factors that include female sex, older age, heart failure ...
Elena Tomaselli Muensterman, J. Tisdale
semanticscholar   +1 more source

Molecular Surface Engineering of Sulfide Electrolytes with Enhanced Humidity Tolerance for Robust Lithium Metal All‐Solid‐State Batteries

Advanced Materials, EarlyView.
It is demonstrated that the electrochemical, interfacial, and humidity stability of halide‐doped sulfide electrolytes (LPSClBr) is significantly enhanced by an organic surface coating using octadecyl phosphonic acid (OPA) and its lithiated form (Li‐OPA). This single‐step strategy enables robust interfacial protection, supports lithium metal anodes, and
Laras Fadillah, Leonie Braks, Jihoon Oh, Mingliang Liu, Hanna Türk, Davide Tisi, Mounir Mensi, Michele Ceriotti, Jang Wook Choi, Ali Coskun   +9 more
wiley   +1 more source

Haloperidol affects coupling between QT and RR intervals in guinea pig isolated heart

Journal of Pharmacological Sciences, 2019
Prolonged QT interval is an independent risk factor for development of ventricular arrhythmias. Haloperidol is one of the drugs inducing QT prolongation.
Petr Vesely, Tibor Stracina, Miroslava Hlavacova, Josef Halamek, Jana Kolarova, Veronika Olejnickova, Veronika Mrkvicova, Hana Paulova, Marie Novakova   +8 more
doaj   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source