Results 151 to 160 of about 30,871 (260)

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

When Rhythm Control Backfires: A Case of Severe QT Prolongation and Polymorphic Ventricular Tachycardia Following Dual Antiarrhythmic Therapy. [PDF]

Cureus
Sapkota S, Balasubramanian A, Vishakh P, Ruck L, Siddiqui T.   +4 more
europepmc   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine. [PDF]

Front Med (Lausanne)
Wu M, Xie L, Lan P, Chen M.
europepmc   +1 more source

Rosmarinus officinalis essential oil components promote anaesthesia in Colossoma macropomum (Cuvier, 1818) through behavioural and cardiorespiratory modulation

Journal of Fish Biology, EarlyView.
Abstract Anaesthetic management plays a crucial role in maintaining the welfare and physiological stability of fish during routine aquaculture and research procedures. The essential oil of Rosmarinus officinalis (ROEO) has emerged as a promising natural anaesthetic; however, its cardiophysiological effects in Amazonian species remain underexplored ...
Lorena Cristina Nunes de Almeida, Axell Lins, Daniella Bastos de Araújo, Maria Klara Otake Hamoy, Marcelo Victor dos Santos Brito, Luana Vasconcelos de Souza, Sarah Farias Câmara, Luciana Eiro Quirino, Nilton Akio Muto, Moisés Hamoy   +9 more
wiley   +1 more source

Case Report: Association of a rare single nucleotide variant in the KCNH2 gene with drug-induced QT prolongation. [PDF]

Front Genet
Wang T, Norgan Radler CR, Sathyamoorthy M.   +2 more
europepmc   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi-Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death. [PDF]

Clin Cardiol
Farjam M, Yazdanpanah MH, Fereydouni N.
europepmc   +1 more source

Concurrent Use of Tasipimidine Oral Solution and Fluoxetine in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This exploratory randomized crossover study investigated pharmacokinetic interactions, functional alertness, and cardiovascular safety of tasipimidine oral solution administered alone and in combination with fluoxetine in healthy Beagle dogs (n = 8; 4 dogs per dose level), with a 7‐day washout between phases. Dogs received single oral doses of
Jenni Lindstedt, Jouko M. Levijoki, Johanna Tuunainen, Jens Häggström, Meri Ramela, Mira Korpivaara   +5 more
wiley   +1 more source

QT prolongation risk factors and a monitoring strategy in rifampicin-resistant tuberculosis: Findings from the STREAM Stage 2 trial. [PDF]

PLOS Glob Public Health
Hughes G, Frangou E, Bern H, Gurumurthy M, Tsogt B, Chiang CY, Nunn AJ, Meredith SK, Goodall RL, STREAM Trial Collaboration.   +9 more
europepmc   +1 more source