Results 171 to 180 of about 55,181 (324)

Issues in QT interval measurement

Indian Pacing and Electrophysiology Journal, 2004
The QT interval, apart from clinical implications is crucial for safety assessment of new drugs under development. A QTc prolongation of even 10 msec in a study group is a warning signal for a new drug.
Pallavi Lanjewar, Vaishali Pathak, Yash Lokhandwala   +2 more
doaj  

Association of Torsade de Pointes and QT Prolongation With Antifungal Triazoles: Analysis Using a Pharmacovigilance Database. [PDF]

In Vivo, 2023
Ohyama K, Akiyama S, Iida M, Hori Y.
europepmc   +1 more source

Clinical outcomes and safety in patients with lower‐risk myelodysplastic syndromes treated with imetelstat: Substudy of the phase 3 IMerge trial

British Journal of Haematology, EarlyView.
Rami S. Komrokji, Valeria Santini, Uwe Platzbecker, Koen Van Eygen, María Díez‐Campelo, Raquel de Paz, Guillermo Sanz Santillana, Sylvain Thépot, Maciej Kaźmierczak, Esther Natalie Oliva, Mikkael A. Sekeres, Pierre Fenaux, Yazan F. Madanat, Michael R. Savona, Jennifer Riggs, Sheetal Shah, Ashley L. Lennox, Qi Xia, Libo Sun, Tymara Berry, Amer M. Zeidan   +20 more
wiley   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Older Age Is Associated With Long‐Term Retention in Buprenorphine Treatment for Opioid Use Disorder

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Opioid use disorder (OUD) among older adults is a fast‐growing public health problem. However, little is known about treatment outcomes among older adults in office‐based buprenorphine programs. Thus, our objective was to examine how age is associated with buprenorphine treatment outcomes among adults with OUD who initiate ...
Justina L. Groeger, Tiffany Lu, Andrea Jakubowski, Chenshu Zhang, Yuting Deng, Hector Perez, Frank DiRenno, Benjamin M. Jadow, Benjamin T. Hayes, Shadi Nahvi, Chinazo O. Cunningham, Joanna L. Starrels   +11 more
wiley   +1 more source

QT Prolongation Following Premature Ventricular Contractions Leading to Ventricular Storms: A Case Report. [PDF]

Cureus
Jalabadze K, Tsiklauri B.
europepmc   +1 more source

Pheochromocytoma presenting with QT prolongation and catecholamine-induced myocarditis in a child. [PDF]

Ann Pediatr Cardiol, 2023
Saengsin K, Sethasathien S, Dejkhamron P, Sittiwangkul R, Makonkawkeyoon K, Silvilairat S, Wejaphikul K, Pongprot Y.   +7 more
europepmc   +1 more source

Does terfenadine‐induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes? [PDF]

, 2012
Hua Rong Lu, An N. Hermans, David J. Gallacher   +2 more
openalex   +1 more source

QT interval prolongation and Torsades de Pointes with donepezil, rivastigmine and galantamine [PDF]

, 2020
Katie Malone, Jules C. Hancox
openalex   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source