Results 1 to 10 of about 40,628 (317)
Fine mapping of multiple QTL using combined linkage and linkage disequilibrium mapping – A comparison of single QTL and multi QTL methods [PDF]
Genetics Selection Evolution, 2007 Two previously described QTL mapping methods, which combine linkage analysis (LA) and linkage disequilibrium analysis (LD), were compared for their ability to detect and map multiple QTL.
Meuwissen Theo HE, Uleberg Eivind
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Integration of QTL mapping and GWAS reveals the complicated genetic architecture of chemical composition traits in tobacco leaves. [PDF]
Front Plant SciUllah A +9 more
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postQTL: a QTL mapping R workflow to improve the accuracy of true positive loci identification
BMC Research Notes, 2022 Objective The determination of the location of quantitative trait loci (QTL) (i.e., QTL mapping) is essential for identifying new genes. Various statistical methods are being incorporated into different QTL mapping functions.
Prashant Bhandari, Tong Geon Lee
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Behavior Genetics, 2004 The standard variance components method for mapping quantitative trait loci is derived on the assumption of normality. Unsurprisingly, statistical tests based on this method do not perform so well if this assumption is not satisfied. We use the statistical concept of copulas to relax the assumption of normality and derive a test that can perform well ...
Basrak, B. +4 more
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R/qtl: high-throughput multiple QTL mapping [PDF]
Bioinformatics, 2010 AbstractMotivation: R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of experimental cross types. We recently added multiple QTL mapping (MQM) to R/qtl.
Arends, D. +3 more
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Joint QTL linkage mapping for multiple-cross mating design sharing one common parent. [PDF]
PLoS ONE, 2011 BackgroundNested association mapping (NAM) is a novel genetic mating design that combines the advantages of linkage analysis and association mapping. This design provides opportunities to study the inheritance of complex traits, but also requires more ...
Huihui Li +4 more
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Inclusive Composite Interval Mapping of QTL by Environment Interactions in Biparental Populations. [PDF]
PLoS ONE, 2015 Identification of environment-specific QTL and stable QTL having consistent genetic effects across a wide range of environments is of great importance in plant breeding. Inclusive Composite Interval Mapping (ICIM) has been proposed for additive, dominant
Shanshan Li, Jiankang Wang, Luyan Zhang
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Scientific Reports, 2023 In recent years multi-parental mapping populations (MPPs) have been widely adopted in many crops to detect quantitative trait loci (QTLs) as this method can compensate for the limitations of QTL analyses using bi-parental mapping populations.
Buddhika A. Dahanayaka, Anke Martin
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QTL Mapping Under Ascertainment [PDF]
Annals of Human Genetics, 2006 SummaryMapping quantitative trait loci (QTL) using ascertained sibships is discussed. It is shown that under the standard normality assumption of variance components analysis the efficient scores are unchanged by ascertainment, and two different schemes of ascertainment correction suggested in the literature are asymptotically equivalent.
J, Peng, D, Siegmund
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Human QTL linkage mapping [PDF]
Genetica, 2008 Human quantitative trait locus (QTL) linkage mapping, although based on classical statistical genetic methods that have been around for many years, has been employed for genome-wide screening for only the last 10-15 years. In this time, there have been many success stories, ranging from QTLs that have been replicated in independent studies to those for
Laura, Almasy, John, Blangero
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